Unique deep ultraviolet-ozone conversion of PDMS to silica enables fast fabrication of glass microstructures at low temperature.

‘3D Pin’ technique helps researchers form stable bonds between suspended nanocrystals to create robust 3D structures.

Year 2020 face_with_colon_three

Ah, Memories! They can be some of our best assets or our most painful tormentors. Good memories give us a sensation of warmth and hope for better times, but bad memories can cause serious trauma.

In this study we aimed to detect epigenetic and genetic loci associated with PTSD in a homogeneous cohort of traumatized police officers. Both a genome-wide and hypothesis-driven replication approach did not result in DMPs between PTSD patients and trauma-exposed controls. GSE analysis on the top 100 DMPs showed, however, a plausible association of the dopaminergic neurogenesis pathway with PTSD. Furthermore, we observed one DMR located at the PAX8 gene suggesting consistent hypermethylation in PTSD patients. Genetic analyses yielded three CpG-SNPs significantly associated with PTSD. Of these, one CpG-SNP, located at the CACNA1C locus, was also significantly associated with PTSD in an independent replication sample of trauma-exposed children. Notably, this result shows that the Illumina 450K array is not restricted to epigenetic surveys but can provide informative genetic data as well.

Although our sample was small, it was highly homogenous as all participants were former or current police officers, and cases and controls were matched for sex, age, education, and years of police service. All participants reported multiple prior traumatic events, without significant group differences in reported types of traumatic experiences. PTSD patients fulfilled current diagnostic criteria for PTSD, while our trauma-exposed controls had minimal PTSD symptoms and did not report lifetime PTSD or other trauma-related psychiatric disorders. Thus our controls were apparently resilient to adverse mental health outcome of trauma. This study design, including extreme phenotypes following similar trauma load, was considered to favor detection of PTSD-associated loci, as also suggested by others [22]. Nevertheless, our genome-wide survey clearly remains limited in statistical power.

Indian start-up Green Robot Machinery (GRoboMac) has developed a cotton picker with autonomous robotic arms, mounted on a semi-autonomous electric farm vehicle.

The robotic arms of the battery-operated machine are each capable of picking about 50 kgs cotton per day. That means that four arms, mounted on the vehicle, can pick about 200 kgs per day. High yielding farms can use additional arms, the company says.

Nano electron guns can help zap cancers and drive new classes of lasers.

In 1,895, Wilhelm Röntgen discovered X-rays and used them to image the bones in his wife’s hand, kicking off a revolutionary diagnostic tool for medicine. Now two of NASA’s X-ray space telescopes have combined their imaging powers to unveil the magnetic field “bones” of a remarkable hand-shaped structure in space. Together, these telescopes reveal the behavior of a dead collapsed star that lives on through plumes of particles of energized matter and antimatter.

Around 1,500 years ago, a giant star in our galaxy ran out of nuclear fuel to burn. When this happened, the star collapsed onto itself and formed an extremely dense object called a neutron star.

Rotating neutron stars with strong magnetic fields, or pulsars, provide laboratories for extreme physics, with conditions that cannot be replicated on Earth. Young pulsars can create jets of matter and antimatter moving away from the poles of the pulsar, along with an intense wind, forming a “pulsar wind nebula.”

Despite its recent discovery in Vietnam, the newt is considered endangered. Learn more about crocodile newts and this recent research.

Travis Gienger is a talented gourd-grower, and he’s used to earning accolades for his colossal pumpkins. Since 2020, he’s won three of the past four World Championship Pumpkin Weigh-Off competitions—and this year’s entry topped them all. Weighing in at 2,749 pounds, Gienger’s gourd has set a new world record for the heaviest pumpkin.

Nicknamed “Michael Jordan,” the pumpkin took the crown during the annual championship in Half Moon Bay, California, this week, reports Heidi Raschke of Minnesota Public Radio (MPR). It easily beat out last year’s champion—Gienger’s own 2,560-pounder, which set a new North American record and which he later turned into the world’s largest jack o’lantern.

“I was not expecting that. It was quite the feeling,” says Gienger, a 43-year-old landscape and horticulture teacher at Anoka Technical College, to the Associated Press (AP). He has been growing pumpkins since he was a teenager, following in the footsteps of his father.

O.o!!!!

Cybrothel.

“We are the future of sex,” says Philipp Fussenegger–owner of Cybrothel is the first immersive sex doll brothel in Germany’s capital city Berlin.