Neurons, the main cells that make up our brain and spinal cord, are among the slowest cells to regenerate after an injury, and many neurons fail to regenerate entirely. While scientists have made progress in understanding neuronal regeneration, it remains unknown why some neurons regenerate and others do not.

Using single-cell RNA sequencing, a method that determines which genes are activated in individual cells, researchers from University of California San Diego School of Medicine have identified a new biomarker that can be used to predict whether or not neurons will regenerate after an injury. Testing their discovery in mice, they found that the biomarker was consistently reliable in… More.

Researchers from University of California San Diego have identified a new biomarker that can predict whether or not neurons will regenerate after an injury. The findings could help scientists develop regenerative therapies for spinal cord injuries and other neurological conditions.

Before epilepsy was understood to be a neurological condition, people believed it was caused by the moon, or by phlegm in the brain. They condemned seizures as evidence of witchcraft or demonic possession, and killed or castrated sufferers to prevent them from passing tainted blood to a new generation.

Today we know epilepsy is a disease. By and large, it’s accepted that a person who causes a fatal traffic accident while in the grip of a seizure should not be charged with murder.

That’s good, says Stanford University neurobiologist Robert Sapolsky. That’s progress. But there’s still a long way to go.

After more than 40 years studying humans and other primates, Sapolsky has reached the… More.

You may think you chose to read this, but Stanford scientist Robert Sapolsky would disagree. He says virtually all human behavior is beyond our conscious control.

Dementia affects more than 55 million people around the world.

A number of factors can increase a person’s risk of developing dementia, including high blood pressure, poor sleep, and physical inactivity.

Meanwhile, keeping cognitively, physically, and socially active, and limiting alcohol consumption, can reduce the risk.

Recently, a large Swedish study observed that chronic stress and depression were linked to a higher risk of developing Alzheimer’s disease, the most common form of dementia. The researchers found people with a history of both chronic stress and depression had an even greater risk of the disease.

Globally, around 280 million people have depression, while roughly 300 million… More.

A study conducted in Japan has found that individuals exhibiting strong autistic traits are often inclined towards dichotomous thinking. The research suggests that these autistic traits might lead to a heightened intolerance of uncertainty, subsequently increasing the propensity for dichotomous thinking. The study was published in Scientific Reports.

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by a wide range of symptoms and challenges. Individuals with autism spectrum disorder typically have restricted interests, difficulties in social interaction and communication. The severity of these challenges can vary greatly from person to person. Some individuals with ASD may have significant language delays and struggle with everyday social interactions, while others may have milder symptoms and excel in certain areas, such as mathematics or art.

Aside from atypical social functioning, autistic individuals tend to exhibit a thinking pattern known as dichotomous, “black-and-white”, or binary thinking. This is a form of cognitive distortion wherein an individual perceives things in a binary way – either black or white, good or bad. There is no middle zone or space for any nuances. The result of this thinking pattern is that the person oversimplifies very complex issues, leading often to inappropriate or obviously poor decisions.

The human brain can change – but usually only slowly and with great effort, such as when learning a new sport or foreign language, or recovering from a stroke. Learning new skills correlates with changes in the brain, as evidenced by neuroscience research with animals and functional brain scans in people. Presumably, if you master Calculus 1, something is now different in your brain. Furthermore, motor neurons in the brain expand and contract depending on how often they are exercised – a neuronal reflection of “use it or lose it.”

People may wish their brains could change faster – not just when learning new skills, but also when overcoming problems like anxiety, depression and addictions.

… More

Change in the brain usually comes with plenty of effort over time. Neuroscientists are working to understand how psychedelic drugs provide a shortcut that seems to rely on existing brain systems.

Tiny, brainless jellyfish just did something that on the surface may seem impossible: the adorable creatures showed evidence of learning.

Even with just 1,000 neurons active at a time and no central brain, Caribbean box jellyfish (Tripedalia cystophora) can learn from experience, researchers argue in a new paper published September 22 in the journal Current Biology. The results aren’t surprising, say several scientists not involved in the project, but are a reminder for people to think more broadly about learning.

“If you’re an animal and have to navigate the world, you have to learn cues and consequences. Otherwise you’re dead, and you can’t reproduce,” says Christie Sahley, a… More.

Human scientists—used to the benefits of a centralized, complex brain—have been underestimating what a simple nerve network can do.

Could changing your diet play a role in slowing or even preventing the development of dementia? We’re one step closer to finding out, thanks to a new UNLV study that bolsters the long-suspected link between gut health and Alzheimer’s disease.

The analysis — led by a team of researchers with the Nevada Institute of Personalized Medicine (NIPM) at UNLV and published this spring in the Nature journal Scientific Reports — examined data from dozens of past studies into the belly-brain connection. The results? There’s a strong link between particular kinds of gut bacteria and Alzheimer’s disease.

UNLV study pinpoints 10 bacterial groups associated with Alzheimer’s disease, provides new insights into the relationship between gut makeup and dementia.

The University of Alberta is 3rd in the world for AI research.

Researchers meet the challenge of developing a model that uses speech traits to detect cognitive decline, paving the way for a potential screening tool.

Researchers are striving to make earlier diagnosis of Alzheimer’s dementia possible with a machine learning (ML) model that could one day be turned into a simple screening tool anyone with a smartphone could use.

The model was able to distinguish Alzheimer’s patients from healthy controls with 70 to 75 per cent accuracy, a promising figure for the more than 747,000 Canadians who have Alzheimer’s or another form of dementia.

A machine learning model able to screen individuals with Alzheimer’s dementia from individuals without it by examining speech traits typically observed among people with the disease could one day become a tool that makes earlier diagnosis possible.

The study’s authors compared the influence of two components of the brain’s physical structure: the outer folds of the cerebral cortex — the area where most higher-level brain activity occurs — and the connectome, the web of nerves that links distinct regions of the cerebral cortex. The team found that the shape of the outer surface was a better predictor of brainwave data than was the connectome, contrary to the paradigm that the connectome has the dominant role in driving brain activity. “We use concepts from physics and engineering to study how anatomy determines function,” says study co-author James Pang, a physicist at Monash University in Melbourne, Australia.

A model of the brain’s geometry better explains neuronal activity than a model based on the ‘connectome’.

Opting for olive oil could reduce your risk of fatal dementia, according to a new study.

Participants who included half a tablespoon of olive oil in their daily diet were 28% less likely to die of dementia.

The study authors found that replacing a single teaspoon of margarine or mayonnaise with olive oil reduced the risk of fatal dementia by 8–14%.

Researchers have observed an association between daily consumption of olive oil — instead of margarine or mayonnaise — and a reduced risk of dying from dementia.

According to the World Health Organization (WHO)Trusted Source, there are over 55 million people living with dementia globally. There are an estimated 10 million new cases yearly, and dementia is also the seventh leading cause of death among older adults.

New research shows that a half tablespoon of olive oil per day may be beneficial for brain health. The study found that replacing a single teaspoon of margarine or mayonnaise with olive oil reduced the risk of fatal dementia by 8–14%.