Until now, it was not clear how hepatocytes were assigned tasks related to their localization. Researchers at the Spanish National Cancer Research Center (CNIO) have discovered that a gene, mTOR, is responsible for organizing the hepatocyte position map.

They also found that what triggers hepatocyte specialization is feeding after birth. The difference is marked by how nutrients reach the organism before and after birth: with no interruptions through the umbilical cord in one case, or in an intermittent fashion –when eating– in the other. The alternation of periods with and without available nutrients activates the mTOR gene and causes the hepatocytes to specialize, which completes the maturation of the liver.

The company’s long-lasting products may even help cut down on discarded food, around a third of which is tossed globally every year.

That waste then releases methane, a powerful heat-trapping gas, as it goes through the process of breaking down in landfills, contributing to rising global temperatures linked to extreme weather events that frequently cause displacement or damage vital food crops.

According to Packaging Digest, even though foodberries are perishable, they are safe and tasty to eat for anywhere from 60 to 90 days, though frozen items can last for more than a year.

Researchers from Weill Cornell Medicine have discovered that unique bacteria colonize the gut shortly after birth and make the neurotransmitter serotonin to educate gut immune cells that help in preventing allergic reactions to food and the bacteria themselves during early development.

The study published in the journal Science Immunology on March 15, 2024, revealed that bacteria abundant in the guts of newborns produce serotonin, which promotes the development of immune cells called T-regulatory cells or Tregs. These cells suppress inappropriate immune responses to help prevent autoimmune diseases and dangerous allergic reactions to harmless food items or beneficial gut microbes.

“The gut is now known as the second human brain as it makes over 90 percent of the neurotransmitters in the human body. While neurotransmitters such as serotonin are best known for their roles in brain health, receptors for neurotransmitters are located throughout the human body,” explained the study’s senior author, Dr. Melody Zeng, an assistant professor of immunology in the Gale and Ira Drukier Institute for Children’s Research and the Department of Pediatrics at Weill Cornell Medicine.

Scientists are embarking on a £1.1 million project aimed at revolutionising drug production by using food by-products to develop new antimicrobial drugs.

Led by the University of Strathclyde in collaboration with the University of Surrey and GSK, the research endeavours to make antimicrobial production more cost-effective and sustainable, thereby addressing the pressing global challenge of antimicrobial resistance.

The project seeks to leverage bacteria, particularly Streptomyces, known for their potential to produce various drugs including antimicrobials. By harnessing food by-products, the team is aiming to device a less carbon-intensive process for biomanufacturing, which could pave the way for a range of medications including anti-parasitic, anti-cancer, anti-fungal, and immunosuppressant drugs.

Cellulose is the primary component of the cell walls of plants, making it the most common polymer on Earth. It’s responsible for the properties of materials like wood and cotton and is the primary component of dietary fiber, so it’s hard to overstate its importance to humanity.

Given its ubiquity and the fact that it’s composed of a bunch of sugar molecules linked together, its toughness makes it very difficult to use as a food source. The animals that manage to extract significant calories from cellulose typically do so via specialized digestive tracts that provide a home for symbiotic bacteria—think of the extra stomachs of cows and other ruminants.

Amazingly, humans also play host to bacteria that can break down cellulose—something that wasn’t confirmed until 2003 (long after I’d wrapped up my education). Now, a new study indicates that we’re host to a mix of cellulose-eating bacteria, some via our primate ancestry, and others through our domestication of herbivores such as cows. But urban living has caused the number of these bacteria to shrink dramatically.

Diabetic medication has garnered popularity within the last few years. It is not necessarily the need for these medications that is associated with its popularity, but a side effect that most individuals desire: weight loss. Since the advent of drugs that promote rapid weight loss such as Ozempic, Mounjaro, and Wegovy, widespread safety concerns are being raised regarding long-term effects and more immediate risks such as complications during surgery.

Ozempic, Mounjaro, and Wegovy are all part of a class of drugs known as semaglutides, which are glucagon-like peptide-1 receptor agonists or GLP1-RAs. GLP1 receptors are expressed on different cells within tissues and organs including the pancreas. GLP1-RAs help the pancreas release insulin and lower blood sugar levels, which makes these medications very helpful for those with diabetes. However, the stomach also has GLP1 receptors. Consequently, it activates these receptors as well and causes the stomach to digest food at a much slower rate. This delayed gastric emptying results in patients feeling full and not eating as much to lose weight. Additionally, previous literature has found that patients on GLP1-RAs have lower risk of adverse cardiovascular effects, such as heart attack. However, there are limitations to this medication associated with surgery.

Surgeons ask patients to fast before a surgery for a myriad of reasons all pertaining to the safety and success of the surgery. One reason includes that under anesthesia any remaining food in the stomach can come up and flow into the trachea leading to a life-threatening condition referred to as “aspiration pneumonitis”. Physicians and scientists are currently working to avoid this event from occurring and are investigating the risk of aspiration pneumonitis in patients.

The monster fruit is the size of a ping-pong ball and weighs 20.4g, about 10 times the average blueberry.

Bill Gates said current AI models need “data that embodies the expertise,” such as in pharmaceuticals or agriculture, in order to succeed.

A genetically modified cow has produced milk containing human insulin, according to a new study. The proof-of-concept achievement could be scaled up to, eventually, produce enough insulin to ensure availability and reduced cost for all diabetics requiring the life-maintaining drug.

Unable to rely on their own supply due to damaged pancreatic cells, type 1 diabetics need injectable insulin to live. As do some type 2 diabetics. The World Health Organization estimates that of those who require insulin, between 150 and 200 million people worldwide, only about half are being treated with it. Access to insulin remains inadequate in many low-and middle-income countries – and some high-income countries – and its cost and unavailability have been well-documented.

In a newly published study led by the Department of Animal Sciences in the College of Agricultural, Consumer and Environmental Sciences at the University of Illinois Urbana-Champaign and the Universidade de São Paulo, researchers say they may have developed a way of eliminating insulin scarcity and reducing its cost using cows. Yep, cows.

Some dairy farms could turn into lifesaving insulin factories.