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An increase in cancers among people 55 years old and younger may be related to accelerated aging in recent generations, according to a study presented at a conference earlier this month.

Experts say years of research support this, though more questions remain to be answered.

Researchers from the Washington University in St. Louis’s medical school presented the findings from their study on accelerated aging earlier this month at the American Association for Cancer Research Annual Meeting.

Taking mouse lifespan to the next levelmoderatorcaitlin lewisspeakersdanique wortel / aubrey de grey / brian kennedy10:30 AM.

A landmark new study confirms that growing a human being in nine months takes a toll—and multiple pregnancies can have a cumulative effect.

Join us on Patreon! https://www.patreon.com/MichaelLustgartenPhDDiscount Links: Epigenetic Testing: https://trudiagnostic.com/?irclickid=U-s3Ii2r7xyIU-LSYLyQ…

Scientists have tested a novel method of providing cells with healthy mitochondria to fight Parkinson’s disease [1].

Parkinson’s disease is the second-most prevalent neurodegenerative disorder, and it affects 10 million people worldwide. The disease is age-related, as its prevalence rises rapidly in people older than 65, although some people are diagnosed much earlier. Parkinson’s disease is characterized by both motor and mental problems: tremor, rigidity (stiffness), and slowness of movement along with memory and thinking deficits.

Parkinson’s disease is caused by the loss of dopamine-producing (dopaminergic) neurons in a brain region called the substantia nigra. Therapeutic options are limited, and some of the existing ones cause nasty side effects.

We depend on our cells being able to divide and multiply, whether it’s to replace sunburnt skin or replenish our blood supply and recover from injury. Chromosomes, which carry all of our genetic instructions, must be copied in a complete way during cell division. Telomeres, which cap the ends of chromosomes, play a critical role in this cell-renewal process—with a direct bearing on health and disease.

Researchers from Washington University School of Medicine suggest accelerated biological aging may be driving early-onset cancer rates in young people.

Is Chief Impact Officer for StartUp Health’s Alzheimer’s Moonshot (https://www.startuphealth.com/alzheimers), a new global initiative created to develop a collaborative innovation community alongside leading companies, research teams, and stakeholders, with a mission to accelerate progress in prevention, diagnosis, and management of Alzheimer’s disease and related dementias. With support from the Alzheimer’s Drug Discovery Foundation (ADDF) and Gates Ventures, StartUp Health is looking to break down silos and foster meaningful collaboration between mission-aligned founders, funders, and partners.

Dr. Ferrell also serves as Strategic Advisor, Davos Alzheimer’s Collaborative (https://www.davosalzheimerscollaborat…) which is building a global clinical trial network and technology platform that will link trial sites around the world.

Continue reading “Dr. Phyllis Ferrell, DrPH, MBA — Chief Impact Officer, Alzheimer’s Moonshot, StartUp Health” »

The extracellular matrix is an essential component of the tumor microenvironment and affects cancer progression. Weeraratna and colleagues have now uncovered that age-related reductions in the level of hyaluronan and proteoglycan link protein 1 (HAPLN1) stimulate neoangiogenesis and compromise the vascular integrity of intratumoral blood vessels. These biological modifications converge to fuel distant melanoma metastasis.