Lifeboat Foundation

A new work by the Nanomol Group, belonging to the CIBER-BBN network, together with a team from the University of Rome Tor Vergata, presents new nanovesicles capable of crossing biological barriers such as cell membranes, while maintaining their sensing capacity, which makes them attractive probes for intracellular detection of biomarkers.

“The development of probes capable of sensing the biological environment and signaling the presence of a specific target molecule is a challenge with relevance in a variety of biomedical applications, from drug delivery to diagnostic tools,” says Mariana Köber, ICMAB researcher and corresponding author of the study, together with Nora Ventosa, from ICMAB, and Alessandro Porchetta, from the University of Rome Tor Vergata.

This work, which has been published in Advanced Functional Materials, presents the design of fluorescent nanovesicles functionalized with biomimetic DNA capable of translating their binding to a target molecule into an optical output, through a change in Förster resonance energy transfer (FRET) and fluorescent emission.

Moke International makes the car in Britain before final assembly in France. The revised chassis has been re-engineered to accommodate four passengers, and look for an all-electric version to be released in the summer. Priced from around $30,000, the Moke can be customized with a choice of 13 colors, including eye-popping Flamingo Pink and Florida Orange. My tester also wears gleaming chrome trim and badging on the hood.

Other stylistic touches include leather hood straps and a retro radio, which is actually able to be heard above the wind noise, at least at speeds below 45 mph. And on a wet day, with weather equipment in place, the windscreen can be heated for improved visibility. In all, this upgraded version is not far off from Sir Alec’s initial car—basic in the extreme and as quintessentially British as fish and chips or a warm pint of beer.

Accordingly, it is reportedly telling customers how to bypass its “genuine” ink bullshit. (translation)

We value you as a customer and a constant user of Canon products. Due to the persistent global shortage of semiconductor components, Canon is currently facing challenges in sourcing certain electronic components that are used in our consumables for our multifunction printers (MFP). These components lead e.g. B. Features such as the detection of the remaining toner level. In order to ensure a continuous and reliable supply of consumables, we have decided to deliver consumables without semiconductor components until normal supply is restored. There is no negative impact on print quality when using consumables without electronic components, but certain additional functions, such as e. B. the detection of the toner level may be impaired.

The instructions appear to be straightforward—for the models I checked all you have to do is ignore onerous error messages—so it seems incorrect to claim Canon blocks the use of third-party cartridges. HP’s ink DRM is clearly more despised —they not only block non-DRM ink, but the ink is region locked and they expect you to pay for and maintain a subscription to it.

Continue reading “Forced: Printer ink company Canon was forced by the silicon shortage to sell cartridges without the DRM chips used to dissuade customers from using third-party tanks” »

Roy Hill has become the first purchaser of Wabtec’s FLXdrive battery-electric locomotive.

In a scene straight out of a spy movie, an elderly couple reportedly escaped from an assisted living facility using some cunning military expertise—and an antiquated telecommunications method.

On March 2, 2020, a resident of a secure memory care unit in Elmcroft of Lebanon, a Tennessee nursing facility, “eloped” with his wife from the premises, according to a state report on the incident. (The Tennessean first reported the incident last month.) The man was admitted to Elmcroft with a diagnosis of dementia, while the woman was admitted with Alzheimer’s disease.

A stranger spotted the residents, who were safe, walking two blocks from Elmcroft about 30 minutes after they left and picked them up.

Continue reading “Dementia Patients Used Morse Code Training to Escape From a Senior Living Facility” »

Methane tank sections were moved into the High Bay as SpaceX prepares to fully stack Booster 7. Meanwhile, crews were spotted using the Klemm drill rig at the Launch Site once again.

Video and Pictures from Mary (@BocaChicaGal) and Nic (@nicansuini). Edited by Patrick Colquhoun (@Patrick_Colqu).

Continue reading “Booster 7 Methane Tank Sections Ready for Stacking | SpaceX Boca Chica” »

Brooklyn, New York-based Tarform Motorcycles began sketching out designs for its slick-looking electric motorcycles almost five years ago. Despite pandemic-related setbacks that delayed production, the company is now beginning deliveries on its first electric motorcycles.

These aren’t just any run-of-the-mill bikes though.

Unlike many of the electric motorcycles we see today that take on a more conventional design intended to please the widest audience, Tarform focused on a more bespoke, hand-made direction from the beginning.

Continue reading “Tarform begins delivering its slick-looking US-built electric motorcycles” »

The number of malware infections targeting Linux devices rose by 35% in 2021, most commonly to recruit IoT devices for DDoS (distributed denial of service) attacks.

IoTs are typically under-powered “smart” devices running various Linux distributions and are limited to specific functionality. However, when their resources are combined into large groups, they can deliver massive DDoS attacks to even well-protected infrastructure.

Besides DDoS, Linux IoT devices are recruited to mine cryptocurrency, facilitate spam mail campaigns, serve as relays, act as command and control servers, or even act as entry points into corporate networks.

Continue reading “Linux malware sees 35% growth during 2021” »

Microsoft has pulled the January Windows Server cumulative updates after critical bugs caused domain controllers to reboot, Hyper-V to not work, and ReFS volume systems to become unavailable.

Tuesday, Microsoft released the January 2022 Patch Tuesday updates for Windows Server that includes numerous security updates and bug fixes.

These updates are KB5009624 for Windows Server 2012 R2, KB5009557 for Windows Server 2019, and KB5009555 for Windows Server 2022.

Continue reading “Microsoft pulls new Windows Server updates due to critical bugs” »