Some research suggests macrophages might be the best target for senescent cell therapies. Here is Mantas from cell age answering a reader question “Are senescent macrophages the problem of other cell types?”
Mantas from CellAge answers a question from one of our readers who asked if senescent macrophages (the cleaner cells of the body) should be the focus of senescent cell removal. Some research this year by Gudkov et al. suggests that macrophages become tainted by senescent cell signals and become dysfunctional and that removing them could be beneficial as they could be replaced with macrophages that do work properly.
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