Archive for the ‘bioprinting’ category

Mar 22, 2024

From Neuronal Differentiation of iPSCs to 3D Neuro-Organoids: Modelling and Therapy of Neurodegenerative Diseases

Posted by in categories: 3D printing, bioprinting, biotech/medical, neuroscience

In the last decade, the advances made into the reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) led to great improvements towards their use as models of diseases. In particular, in the field of neurodegenerative diseases, iPSCs technology allowed to culture in vitro all types of patient-specific neural cells, facilitating not only the investigation of diseases’ etiopathology, but also the testing of new drugs and cell therapies, leading to the innovative concept of personalized medicine. Moreover, iPSCs can be differentiated and organized into 3D organoids, providing a tool which mimics the complexity of the brain’s architecture. Furthermore, recent developments in 3D bioprinting allowed the study of physiological cell-to-cell interactions, given by a combination of several biomaterials, scaffolds, and cells.

Mar 9, 2024

3D-printed skin closes wounds and contains hair follicle precursors

Posted by in categories: 3D printing, bioprinting, biotech/medical, engineering

Science: In future maybe wounds be cured and closed in seconds by 3D printing regeneration.

Fat tissue holds the key to 3D printing layered living skin and potentially hair follicles, according to researchers who recently harnessed fat cells and supporting structures from clinically procured human tissue to precisely correct injuries in rats. The advancement could have implications for reconstructive facial surgery and even hair growth treatments for humans.

The team’s findings were published March 1 in Bioactive Materials. The U.S. Patent and Trademark Office granted the team a patent in February for the bioprinting technology it developed and used in this study.

Continue reading “3D-printed skin closes wounds and contains hair follicle precursors” »

Feb 17, 2024

Fluicell partners with Swedish researchers to 3D bioprint complex brain cell structures

Posted by in categories: 3D printing, bioprinting, biotech/medical, neuroscience

Scientists from medical tech company Fluicell have partnered with clinical R&D firm Cellectricon and the Swedish Karolinska Institutet university to 3D bioprint neural cells into complex patterns.

Using the microfluidic printheads featured on Fluicell’s Biopixlar platform, the researchers were able to accurately arrange rat brain cells within 3D structures, without damaging their viability. The resulting cerebral tissues could be used to model the progress of neurological diseases, or to test the efficacy of related drugs.

“We’ve been using Biopixlar to develop protocols for the printing of different neuronal cells types, and we are very pleased with its performance,” said Mattias Karlsson, CEO of Cellectricon. “This exciting technology has the potential to open completely new avenues for in-vitro modeling of a wide range of central and PNS-related diseases.”

Jan 5, 2024

Regenerative Medicine Using Living Cell Tubes

Posted by in categories: bioprinting, biotech/medical, life extension

😀 They say we could even regenerate human limbs this way aswell as repair human blood vessels.

Cell tubes, made entirely from a patient’s own cells, are just as elastic as blood vessels but much stronger. Skin cells cultured into lumps are skewered on needles on a base, similar to a Kenzan, a tool used in Japanese flower arrangements, and formed into a tube. The technique, called the Kenzan Method, was made possible by a 3D bioprinter. A clinical trial is underway in Japan to transplant these tubes into humans in place of blood vessels. Studies are being done to apply them to nerves and organs.

Nov 26, 2023

Scientists 3D-Print Hair Follicles in Lab-Grown Skin

Posted by in categories: 3D printing, bioprinting, biotech/medical, chemistry, engineering, life extension

The technique represents an important step in engineering skin grafts, drug testing. A team led by scientists at Rensselaer Polytechnic Institute has 3D-printed hair follicles in human skin tissue cultured in the lab. This marks the first time researchers have used the technology to generate hair follicles, which play an important role in skin healing and function.

The finding, published in the journal Science Advances, has potential applications in regenerative medicine and drug testing, though engineering skin grafts that grow hair are still several years away.

“Our work is a proof-of-concept that hair follicle structures can be created in a highly precise, reproducible way using 3D-bioprinting. This kind of automated process is needed to make future biomanufacturing of skin possible,” said Pankaj Karande, Ph.D., an associate professor of chemical and biological engineering and a member of Rensselaer’s Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies, who led the study.

Oct 22, 2023

New 3D-printed tumor model enables faster, less expensive and less painful cancer treatment

Posted by in categories: bioprinting, biotech/medical, computing, mathematics

An international team of interdisciplinary researchers has successfully created a method for better 3D modeling of complex cancers. The University of Waterloo-based team combined cutting-edge bioprinting techniques with synthetic structures or microfluidic chips. The method will help lab researchers more accurately understand heterogeneous tumors: tumors with more than one kind of cancer cell, often dispersed in unpredictable patterns.

The research, “Controlled tumor heterogeneity in a co-culture system by 3D bio-printed tumor-on-chip model,” appears in Scientific Reports.

Traditionally, would biopsy a patient’s tumor, extract cells, and then grow them in flat petri dishes in a lab. “For 50 years, this was how biologists understood tumors,” said Nafiseh Moghimi, an post-doctoral researcher and the lead author of the study. “But a decade ago, repeated treatment failures in made scientists realize that a 2D model does not capture the real tumor structure inside the body.”

Oct 20, 2023

Creating Sapient Technology and Cyborg Rights Should Happen Soon

Posted by in categories: 3D printing, bioengineering, bioprinting, biotech/medical, cyborgs, existential risks, genetics, robotics/AI, transhumanism

Here’s my latest Opinion piece just out for Newsweek…focusing on cyborg rights.

Over the past half-century, the microprocessor’s capacity has doubled approximately every 18–24 months, and some experts predict that by 2030, machine intelligence could surpass human capabilities. The question then arises: When machines reach human-level intelligence, should they be granted protection and rights? Will they desire and perhaps even demand such rights?

Beyond advancements in microprocessors, we’re witnessing breakthroughs in genetic editing, stem cells, and 3D bioprinting, all which also hold the potential to help create cyborg entities displaying consciousness and intelligence. Notably, Yale University’s experiments stimulating dead pig brains have ignited debates in the animal rights realm, raising questions about the ethical implications of reviving consciousness.

Continue reading “Creating Sapient Technology and Cyborg Rights Should Happen Soon” »

Aug 31, 2023


Posted by in categories: bioengineering, bioprinting, biotech/medical, chemistry, cyborgs, food, genetics, robotics/AI, transhumanism

What happens when humans begin combining biology with technology, harnessing the power to recode life itself.

What does the future of biotechnology look like? How will humans program biology to create organ farm technology and bio-robots. And what happens when companies begin investing in advanced bio-printing, artificial wombs, and cybernetic prosthetic limbs.

Continue reading “GENETIC ENGINEERING & BIOTECHNOLOGY in the Future (2077 & Beyond)” »

Aug 12, 2023

Cutting Edge Levitation Technologies Aim to Revolutionize Bioprinting and Space Travel

Posted by in categories: bioprinting, biotech/medical, space travel

A new project is using cutting-edge levitation techniques to make bioprinting heart models and other complex tissues a reality.

Dubbed PULSE, the project combines the recently developed techniques of acoustic levitation and magnetic levitation to manipulate individual components without actually touching them. It’s a process that the researchers involved hope will one day facilitate the bioprinting of organs and other human tissues in much greater detail and complexity than what is achievable with current techniques.

If perfected, the researchers also hope this type of bioprinting could even help on long-term space missions as more accurate organ models can create more accurate defenses against radiation and other stresses of space travel.

Jul 30, 2023

Magnetic and acoustic levitation to protect bioprint heart models against radiation

Posted by in categories: bioprinting, biotech/medical, health, space travel

Reducing reliance of aninmal experimentation. 🐀

According to the team, this new unparalleled technology facilitates the precise manipulation of biological materials, enabling the creation of highly sophisticated and realistic organoids that closely mimic the complexity of the corresponding human organs.

The cutting-edge magnetic and acoustic levitation will bioprint heart models to improve protection against radiation both in space and on Earth.

Continue reading “Magnetic and acoustic levitation to protect bioprint heart models against radiation” »

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