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Grigory Tikhomirov | DNA-Based Molecular Manufacturing for Biotech and Electronics

*This video was recorded at ‘Paths to Progress’ at LabWeek hosted by Protocol Labs & Foresight Institute.*

Protocol Labs and Foresight Institute are excited to invite you to apply to a 5-day mini workshop series to celebrate LabWeek, PL’s decentralized conference to further public goods. The theme of the series, Paths to Progress, is aimed at (re)-igniting long overdue progress in longevity bio, molecular nanotechnology, neurotechnology, crypto & AI, and space through emerging decentralized, open, and technology-enabled funding mechanisms.

*This mini-workshop is focused on Paths to Progress in Molecular Nanotechnology*
Molecular manufacturing, in its most ambitious incarnation, would use programmable tools to bring together molecules to make precisely bonded components in order to build larger structures from the ground up. This would enable general-purpose manufacturing of new materials and machines, at a fraction of current waste and price. We are currently nowhere near this ambitious goal. However, recent progress in sub-fields such as DNA nanotechnology, protein-engineering, STM, and AFM provide possible building blocks for the construction of a v1 of molecular manufacturing; the molecular 3D printer. Let’s explore the state of the art and what type of innovation mechanisms could bridge the valley of death: how might we update the original Nanotech roadmap; is a tech tree enough? how might we fund the highly interdisciplinary progress needed to succeed: FRO vs. DAO?

*About The Foresight Institute*

The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1986 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support. From molecular nanotechnology, to brain-computer interfaces, space exploration, cryptocommerce, and AI, Foresight gathers leading minds to advance research and accelerate progress toward flourishing futures.

*We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page:* https://foresight.org/donate/

After last week’s stunning landing, here’s what comes next for Blue Origin

For decades—yes, literally decades—it has been easy to dismiss Blue Origin as a company brimming with potential but rarely producing much of consequence.

But last week the company took a tremendous stride forward, not just launching its second orbital rocket, but subsequently landing the booster on a barge named Jacklyn. It now seems clear that Blue Origin is in the midst of a transition from sleeping giant to force to be reckoned with…

…Limp said success on New Glenn’s second flight would set the company up for a significant increase in cadence. The company is building enough hardware for “well above” a dozen flights in 2026, with the upper-end limit of 24 launches. The pacing item is second stages. Right now Blue Origin can build one per month, but the production rate is increasing.”


“There’s never been such a high demand for launch as there is right now.”

ID830 is the most X-ray luminous radio-loud quasar, observations find

An international team of astronomers have employed the Spektr-RG spacecraft and various ground-based telescopes to investigate a distant quasar known as ID830. Results of the new observations, published November 7 on the pre-print server arXiv, indicate that ID830 is the most X-ray luminous radio-loud quasar known to date.

Quasars, or quasi-stellar objects (QSOs), are (AGN) in the centers of active galaxies, powered by supermassive black holes (SMBHs). They showcase very high bolometric luminosities (over one quattuordecillion erg/s), emitting observable in radio, infrared, visible, ultraviolet and X-ray wavelengths.

SpaceX reveals simpler lander to speed up Moon return

With its metaphorical feet held over the allegorical fire by NASA, SpaceX has released a new, simplified plan to build a lander to put US astronauts back on the Moon now that the competition for the spacecraft has been reopened due to delays.

NASA’s Artemis program to establish a permanent US human presence on the Moon is ambitious beyond any doubt. However, like previous American efforts, it’s been fraught with cost overruns, delays and technical problems. One of the most aggravating of these bottlenecks has been building the lunar lander because if you don’t have a way to actually put astronauts on the actual Moon, you’re pretty much wasting your time.

SpaceX’s original plan was to build a lander based on its still-experimental Starship rocket – more than just based on it, the craft would essentially be a complete, baseline Starship complete with airfoils and heat shields. The goal was to land up to 100 tonnes of supplies on the Moon or enough to establish a complete, sustainable base.

The Lunar Module Descent Engine: Apollo’s Most Complex Rocket Motor

The Lunar Module’s Descent Propulsion System (DPS) was the first engine in history that could throttle continuously in deep space — a breakthrough that made Apollo’s lunar landing possible. This engine had to ignite once, vary its thrust smoothly from 10 to 100 percent, avoid combustion instability, and hold steady while the LM hovered just feet above the Moon.
In this video, we explore the real engineering behind the DPS: its hypergolic fuels, injector plate design, the early “chugging” instability problem, throttle control logic, and how the engine kept working even as Apollo 11 pushed it to its limits.
If you enjoy deep dives into Apollo engineering, this one’s for you.

🚀 Every like, comment, and share helps keep Apollo’s engineering story alive.

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🚀 New Apollo episodes every week!

📘 Recommended Reading for Space Enthusiasts.

Explore the real stories, engineering, and people behind the Apollo Program — these are the best books to deepen your knowledge:

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