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Electron beam method enables precise nanoscale carving and building of copper structures

Creating complex structures at the tiniest scales has long been a challenge for engineers. But new research from Georgia Tech shows how electron beams, already widely used in imaging and fabrication, can also be used as ultra-precise tools to both carve and build structures out of materials like copper.

The research group of Professor Andrei Fedorov at the George W. Woodruff School of Mechanical Engineering has discovered a technique that uses focused electron beams in a liquid environment to either remove or deposit copper, depending entirely on the surrounding chemistry.

By tuning the amount of in the solution, the researchers were able to control whether the beam etched away the material or deposited it, effectively allowing 3D sculpting at the atomic level.

Researchers demonstrate first bidirectional asymmetric frequency conversion in a single system

A research team in Korea has experimentally demonstrated, for the first time in the world, a nonlinear wave phenomenon that changes its frequency—either rising or falling—depending on which direction the waves come from.

Much like Janus, the Roman god with two faces looking in , the system exhibits different responses depending on the direction of the incoming wave. This groundbreaking work opens new horizons for technologies ranging from medical ultrasound imaging to advanced noise control.

The joint research team, led by Professor Junsuk Rho of POSTECH’s Departments of Mechanical Engineering, Chemical Engineering, Electrical Engineering, and the Graduate School of Convergence Science and Technology, along with Dr. Yeongtae Jang, Ph.D. candidate Beomseok Oh, and Professor Eunho Kim of Jeonbuk National University, has experimentally demonstrated a phenomenon of bidirectional asymmetric frequency conversion within a granular phononic crystal system.

Research reveals quantum topological potential in material

New research into topological phases of matter may spur advances in innovative quantum devices. As described in a new paper published in the journal Nature Communications, a research team including Los Alamos National Laboratory scientists used a novel strain engineering approach to convert the material hafnium pentatelluride (HfTe5) to a strong topological insulator phase, increasing its bulk electrical resistance while lowering it at the surface, a key to unlocking its quantum potential.

“I’m excited that our team was able to show that the elusive and much-sought-after topological surface states can be made to become a predominant electrical conduction pathway,” said Michael Pettes, scientist with the Center for Integrated Nanotechnologies (CINT) at the Laboratory.

“This is promising for the development of types of quantum optoelectronic devices, dark matter detectors and topologically protected devices such as quantum computers. And the methodology we demonstrate is compatible for experimentation on other .”

Design strategies for reshaping stability and sustainability of perovskite solar cells

A research team from the School of Engineering (SENG) at the Hong Kong University of Science and Technology (HKUST) has introduced comprehensive bio-inspired multiscale design strategies to address key challenges in the commercialization of perovskite solar cells: long-term operational stability. Drawing inspiration from natural systems, these strategies aim to enhance the efficiency, resilience, and adaptability of solar technologies.

Their paper, titled “Bio-Inspired Multiscale Design for Perovskite Solar Cells,” has been published in Nature Reviews Clean Technology.

The approaches focus on leveraging insights from to create that can better withstand environmental stressors and prolonged use.

In JCI insight: CAR-T cell therapy for solid tumors remains limited

In this Review, Ruoqi Chen et al. discuss the latest advances in transcriptional factor engineering for empowering CAR-T cells with superior antitumor efficacy.


1Eye Center of Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Provincial Key Laboratory of Ophthalmology, Zhejiang Provincial Clinical Research Center for Eye Diseases. Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou, China.

2Liangzhu Laboratory, Zhejiang University, Hangzhou, China.

3Bone Marrow Transplantation Center of the First Affiliated Hospital and Department of Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.

Researchers visualize crystal phase changes particle by particle in new simulations

The secret to how steel hardens and shape-memory alloys snap into place lies in rapid, atomic-scale shifts that scientists have struggled to observe in materials. Now, Cornell researchers are revealing how these transformations unfold, particle by particle, through advanced modeling techniques.

Using custom-built computer simulations, Julia Dshemuchadse, assistant professor of and engineering at Cornell Engineering, and Hillary Pan, Ph.D., have visualized solid-solid phase transitions in unprecedented detail, capturing the motion of every particle in a theoretical material as its crystal structure morphs into another.

Their findings, published in the Proceedings of the National Academy of Sciences, reveal not only classical transformation mechanisms, but also entirely new ones, reshaping how scientists understand this fundamental process in materials science.

Researchers Crack One of Aromatic Chemistry’s Toughest Challenges

A team of scientists has developed an electrochemical technique that enables precise, para-position single-carbon insertion into polysubstituted pyrroles. This advancement holds significant promise for synthetic organic chemistry, particularly in the development of pharmaceutical compounds.

Their work was recently published in the Journal of the American Chemical Society.

“We set out to address the longstanding challenge of achieving single-carbon insertion into aromatic rings with precise positional control,” said Mahito Atobe, Professor, Faculty of Engineering, Yokohama National University.

Goodbye plastic? Scientists create new supermaterial that outperforms metals and glass

Scientists at Rice University and University of Houston have developed an innovative, scalable approach to engineer bacterial cellulose into high-strength, multifunctional materials. The study, published in Nature Communications, introduces a dynamic biosynthesis technique that aligns bacterial cellulose fibers in real-time, resulting in robust biopolymer sheets with exceptional mechanical properties.

Plastic pollution persists because traditional synthetic polymers degrade into microplastics, releasing harmful chemicals like bisphenol A (BPA), phthalates and carcinogens. Seeking sustainable alternatives, the research team led by Muhammad Maksud Rahman, assistant professor of mechanical and aerospace engineering at the University of Houston and adjunct assistant professor of materials science and nanoengineering at Rice, leveraged bacterial cellulose — one of Earth’s most abundant and pure biopolymers — as a biodegradable alternative.

Self-powered solar panels remove dust using wind-generated electricity

A collaborative research team has successfully developed a self-powered pollution prevention technology that can remove pollutants from the surface of solar panels without external power. This technology uses a wind-powered rotational triboelectric nanogenerator to generate power and combines said power with electrodynamic screen (EDS) technology to move dust in the desired direction for removal.

The findings are published in the journal Nano Energy. The team was led by Professor Juhyuck Lee from the Department of Energy Science and Engineering, Daegu Gyeongbuk Institute of Science & Technology, along with Dr. Wanchul Seung at Global Technology Research, Samsung Electronics.

The dust that gathers on the surface of solar panels causes a significant reduction in power production efficiency. EDS technology, designed to address this problem, uses electric fields to remove dust from the surface, and it is noted for environments that are not easily accessible, such as deserts, mountains, and space, as it does not require cleaning equipment or personnel. Traditional EDS technology, however, requires and, consequently, external power, and it has the disadvantage of additional maintenance costs.

‘Universal cancer vaccine’ trains the immune system to kill any tumor

Following on from their breakthrough human trial that successfully reprogrammed the immune system to overpower glioblastoma, an aggressive brain tumor, the same scientists have now further developed the mRNA vaccine to fight not one but any cancer. It has the potential to do away with chemotherapy, surgery and radiation treatment.

University of Florida (UF) scientists have developed an experimental vaccine that dramatically boosts the immune system’s ability to fight tumors – even without targeting a specific cancer type. This “general purpose” mRNA jab works in a similar way to a Covid-19 vaccine but with a different target; it instructs the body’s immune cells to rally and hit any kind of tumor in the same way they would attack a viral spike protein.

“This paper describes a very unexpected and exciting observation: that even a vaccine not specific to any particular tumor or virus – so long as it is an mRNA vaccine – could lead to tumor-specific effects,” said Elias Sayour, a pediatric oncologist and principal investigator at the RNA Engineering Laboratory at UF. “This finding is a proof of concept that these vaccines potentially could be commercialized as universal cancer vaccines to sensitize the immune system against a patient’s individual tumor.”