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Machine learning helps solve a central problem of quantum chemistry

Within the STRUCTURES Cluster of Excellence, two research teams at the Interdisciplinary Center for Scientific Computing (IWR) have refined a computing process, long held to be unreliable, such that it delivers precise results and reliably establishes a physically meaningful solution. The findings are published in the Journal of the American Chemical Society.

Why molecular electron densities matter

How electrons are distributed in a molecule determines its chemical properties—from its stability and reactivity to its biological effect. Reliably calculating this electron distribution and the resulting energy is one of the central functions of quantum chemistry. These calculations form the basis of many applications in which molecules must be specifically understood and designed, such as for new drugs, better batteries, materials for energy conversion, or more efficient catalysts.

The Genius of Computing with Light

Check out shortform and get a FREE trial and $50 OFF the annual plan! at https://www.shortform.com/DrBen.

PsiQuantum are world leaders in the race to utility-scale quantum computing, but they have been shrouded in mystery for over a decade…until now.

Thanks to some good fortune and incredible generosity from the PsiQuantum team I was able to get behind the scenes and see what makes their ground-breaking quantum computer ‘click’

You can see their public paper here: https://www.nature.com/articles/s41586-025-08820-7

0:00 Silicon Valley’s Most Secretive Quantum Computer.
1:38 A Quantum Computer that runs on Light.
6:03 How to Create a Single Photon.
9:00 How to Build a Quantum Clock.
10:48 Ad Read.
11:54 Detecting Single Photons.
15:00 Creating the Perfect Material.
18:19 How to do math with light.
21:45 How to Build a Scalable Quantum Computer.
24:27 Converting Space to Time.
27:25 The First Photonic Quantum Computer Demonstrator.

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Measuring chaos: Researchers quantify the quantum butterfly effect

For the first time, researchers in China have accurately quantified how chaos increases in a quantum many-body system as it evolves over time. Combining experiments and theory, a team led by Yu-Chen Li at the University of Science and Technology of China showed that the level of chaos grows exponentially when time reversal is applied to these systems—matching predictions of their extreme sensitivity to errors. The research has been published in Physical Review Letters.

The butterfly effect is a well-known expression of chaos theory. It describes how a complex system can quickly become unpredictable as it evolves: make just a few small errors when specifying the system’s starting conditions, and it may look completely different from your calculations a short time later.

This effect is especially relevant in many-body quantum systems, where entanglement creates intricate webs of interconnection between particles—even in relatively small systems. As the system evolves, information about its initial state becomes increasingly dispersed across these connections.

Record-breaking photons at telecom wavelengths

A team of researchers from the University of Stuttgart and the Julius-Maximilians-Universität Würzburg led by Prof. Stefanie Barz (University of Stuttgart) has demonstrated a source of single photons that combines on-demand operation with record-high photon quality in the telecommunications C-band—a key step toward scalable photonic quantum computation and quantum communication. “The lack of a high-quality on-demand C-band photon source has been a major problem in quantum optics laboratories for over a decade—our new technology now removes this obstacle,” says Prof. Stefanie Barz.

The key: Identical photons on demand In everyday life, distinguishing features may often be desirable. Few want to be exactly like everyone else. When it comes to quantum technologies, however, complete indistinguishability is the name of the game. Quantum particles such as photons that are identical in all their properties can interfere with each other—much as in noise-canceling headphones, where sound waves that are precisely inverted copies of the incoming noise cancel out the background.

When identical photons are made to act in synchrony, then the probability that certain measurement outcomes occur can be either boosted or decreased. Such quantum effects give rise to powerful new phenomena that lie at the heart of emerging technologies such as quantum computing and quantum networking. For these technologies to become feasible, high-quality interference between photons is essential.

BREAKTHROUGH: How Consciousness Creates the Simulation | Dr. Donald Hoffman

Cognitive Scientist, Dr. Donald Hoffman returns to the mind meld!
Are we, as Plato argued thousands of years ago, mistaking shadows on a cave wall for reality?

In this conversation with the brilliant Dr. Donald Hoffman, we question whether space-time and the world we experience with our senses is fundamental or merely a shallow projection of something deeper. Drawing on Plato’s cave, physics, cognitive science, mystical traditions, quantum theory, and Hoffman’s own framework of conscious agents, we explore the possibility that reality emerges from consciousness rather than the other way around. Don also shares what could be a mind blowing breakthrough in his theory.
What is reality? Will science ever find a final theory of everything? Are we locked inside a simulation designed for survival, not truth? If consciousness transcends space-time, what does that imply about our potential, our perception, our purpose and our fate as beings? We riff on all of this and more in this mind meld.

Links for Donald Hoffman:
New to Don’s work? Start with this TED Talk: https://youtu.be/oYp5XuGYqqY?si=dJJzY05c1koiTYb4
Don’s book, The Case Against Reality: https://a.co/d/0aGapviw.
Don’s UC Irvine page: https://sites.socsci.uci.edu/~ddhoff/

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Why Cybersecurity Strategies and Frameworks Must Be Recalibrated in the Age of AI and Quantum Threats

#cybersecurity #ai #quantum


Artificial intelligence and quantum computing are no longer hypothetical; they are actively altering cybersecurity, extending attack surfaces, escalating dangers, and eroding existing defenses. We are in a new ear of emerging technologies that are directly impacting cybersecurity requirements.

As a seasoned observer and participant in the cybersecurity domain—through my work, teaching, and contributions to Homeland Security Today, my book “Inside Cyber: How AI, 5G, IoT, and Quantum Computing Will Transform Privacy and Our Security”, — I have consistently underscored that technological advancement is outpacing our institutions, policies, and workforce preparedness.

Current frameworks, intended for a pre-digital convergence era, are increasingly unsuitable. In order to deal with these dual-use technologies that act as force multipliers for both defenders and enemies, we must immediately adjust our strategy as time is of the essence.

Novel quantum dynamics with superconducting qubits

The prevailing view is that quantum phenomena can be leveraged to tackle certain problems beyond the reach of classical approaches. Recent years have witnessed significant progress in this direction; in particular, superconducting qubits have emerged as one of the leading platforms for quantum simulation and computation on Noisy Intermediate-Scale Quantum (NISQ) processors. This progress is exemplified by research ranging from the foundations of quantum mechanics to the non-equilibrium dynamics of elementary excitations and condensed matter physics.

By utilizing the contextuality of quantum measurements to solve a 2D hidden linear function problem, we demonstrate a quantum advantage through a computational separation for up to 105 qubits on these bounded-resource tasks. Motivated by high-energy physics, we image charge and string dynamics in (2+1)D lattice gauge theories, revealing two distinct regimes within the confining phase: a weak-confinement regime with strong transverse string fluctuations and a strong-confinement regime where these fluctuations are suppressed. Turning to condensed matter, we observe novel localization in one-and two-dimensional many-body systems that lack energy diffusion despite being disorder-free and translationally invariant. Additionally, we show that strong disorder in interacting multi-level landscapes can induce superfluidity characterized by long-range phase coherence.

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