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Archive for the ‘sex’ category

Nov 12, 2020

Sex with Neanderthals helped modern humans survive, says study

Posted by in categories: biotech/medical, sex

I guess we need to thank our neanderthal forebearers. 😃


A new study shows how interbreeding of modern humans and Neanderthals boosted our genomes.

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Nov 7, 2020

Female-to-male sex conversion in Ceratitis capitata

Posted by in categories: biotech/medical, food, genetics, sex

The Sterile Insect Technique (SIT) is based on the mass release of sterilized male insects to reduce the pest population size via infertile mating. Critical for all SIT programs is a conditional sexing strain to enable the cost-effective production of male-only populations. Compared to current female-elimination strategies based on killing or sex sorting, generating male-only offspring via sex conversion would be economically beneficial by doubling the male output. Temperature-sensitive mutations known from the D. melanogaster transformer-2 gene (tra2ts) induce sex conversion at restrictive temperatures, while regular breeding of mutant strains is possible at permissive temperatures. Since tra2 is a conserved sex determination gene in many Diptera, including the major agricultural pest Ceratitis capitata, it is a promising candidate for the creation of a conditional sex conversion strategy in this Tephritid. Here, CRISPR/Cas9 homology-directed repair was used to induce the D. melanogaster-specific tra2ts SNPs in Cctra2. 100% female to male conversion was successfully achieved in flies homozygous for the tra2ts2 mutation. However, it was not possible, to identify a permissive temperature for the mutation allowing the rearing of a tra2ts2 homozygous line, as lowering the temperature below 18.5 °C interferes with regular breeding of the flies.

Oct 6, 2020

We are approaching the fastest, deepest, most consequential technological disruption in history

Posted by in categories: economics, energy, food, governance, sex, transportation

The next decade is going to be a transforming decade as many many technologies (some of which we all like to share in this group) are converging and maturing enough to rearrange our society in almost any aspect we can conceive.

I’m calling to those who are interested in creating and implementing an alternative model for the current social and governance systems, let’s build an open state that we can all support and trust regardless of our age, sex, geographical location, or belief system.

In the next 10 years, key technologies will converge to completely disrupt the five foundational sectors—information, energy, food, transportation, and materials—that underpin our global economy. We need to make sure the disruption benefits everyone.

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Oct 3, 2020

Cindy Gallop

Posted by in categories: bioengineering, life extension, sex

Founder of MakeLoveNotPorn, and internationally famous advertising executive and public speaker, talks of Sex-Tech, a burgeoning trillion dollar industry, on the ideaXme show — #Ideaxme #MoveTheHumanStoryForward #CindyGallop #MakeLoveNotPorn #SexTech #Sexuality #SociallyAcceptableSex #Pornography #Porn #Orgasm #ErectileDysfunction #Biohacking #Viagra #Wellness #Health #Longevity #DisruptAging #Aarp #IfWeRanTheWorld #BartleBogleHegarty #Advertising #PublicRelations #TEDTalk #IraPastor #Bioquark #Regenerage AARP Disrupt Aging.

Sep 27, 2020

Neanderthal and Denisovan Y Chromosomes Sequenced – Surprise When Compared to Modern Human DNA

Posted by in categories: biotech/medical, sex

Neanderthals have adopted male sex chromosome from modern humans.

In 1997, the very first Neanderthal DNA sequence — just a small part of the mitochondrial genome — was determined from an individual discovered in the Neander Valley, Germany, in 1856. Since then, improvements in molecular techniques have enabled scientists at the Max Planck Institute for Evolutionary Anthropology to determine high quality sequences of the autosomal genomes of several Neanderthals, and led to the discovery of an entirely new group of extinct humans, the Denisovans, who were relatives of the Neanderthals in Asia.

However, because all specimens well-preserved enough to yield sufficient amounts of DNA have been from female individuals, comprehensive studies of the Y chromosomes of Neanderthals and Denisovans have not yet been possible. Unlike the rest of the autosomal genome, which represents a rich tapestry of thousands of genealogies of any individual’s ancestors, Y chromosomes have a peculiar mode of inheritance — they are passed exclusively from father to son. Y chromosomes, and also the maternally-inherited mitochondrial DNA, have been extremely valuable for studying human history.

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Sep 15, 2020

TECHNOCULTURE: The Rise of Man | The Cybernetic Theory of Mind

Posted by in categories: evolution, food, mobile phones, neuroscience, quantum physics, sex

What has been shaping the human mind throughout the history of mankind? What is the difference between mind and consciousness? What links quantum physics to consciousness? What gives rise to our subjective experience? What drives our accelerating evolution?

If you’re eager to familiarize with probably the most advanced ontological framework to date or if you’re already familiar with the Syntellect Hypothesis which, with this series, is now presented to you as the full-fledged Cybernetic Theory of Mind, you should get this book two of the series which corresponds to Part II of The Syntellect Hypothesis: Five Paradigms of the Mind’s Evolution. This volume two contains some newly-introduced and updated material if compared with the originally published version and can be read as a stand-alone book. At the same time, it is highly recommended to obtain The Syntellect Hypothesis as the original coherent version of the same theoretical framework instead of waiting for all five books to come out and if you don’t need extra detailing.

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Sep 14, 2020

New Map Charts Genetic Expression Across Tissue Types, Sexes

Posted by in categories: biotech/medical, genetics, life extension, neuroscience, sex

From the data, the GTEx team could identify the relationship between specific genes and a type of regulatory DNA called expression quantitative trait loci, or eQTL. At least one eQTL regulates almost every human gene, and each eQTL can regulate more than one gene, influencing expression, GTEx member and human geneticist Kristin Ardlie of the Broad Institute tells Science.

Another major takeaway from the analyses was that sex affected gene expression in almost all of the tissue types, from heart to lung to brain cells. “The vast majority of biology is shared by males and females,” yet the gene expression differences are vast and might explain differences in disease progression, GTEx study coauthor Barbara Stranger of Northwestern University’s Feinberg School of Medicine tells Science. “In the future, this knowledge may contribute to personalized medicine, where we consider biological sex as one of the relevant components of an individual’s characteristics,” she says in a statement issued by the Centre for Genome Regulation in Barcelona, where some of the researchers who participated in the GTEx project work.

Another of the studies bolsters the association between telomere length, ancestry, and aging. Telomere length is typically measured in blood cells; GTEx researchers examined it in 23 different tissue types and found blood is indeed a good proxy for overall length in other tissues. The team also showed that, as previously reported, shorter telomeres were associated with aging and longer ones were found in people of African ancestry. But not all earlier results held; the authors didn’t see a pattern of longer telomeres in females or constantly shorter telomeres across the tissues of smokers as previous studies had.

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Sep 5, 2020

This Gene May Be Why Women with Alzheimer’s Disease Live Longer

Posted by in categories: biotech/medical, neuroscience, sex

Women with Alzheimer’s disease tend to live longer than men with the disease — and a new study suggests that a gene on the X chromosome may help explain why.

Each person typically has one pair of sex chromosomes in each cell of their body. People assigned female at birth typically have two X chromosomes, while people assigned male at birth typically have one X chromosome and one Y chromosome.

Researchers say a gene called KDM6A may explain why women with Alzheimer’s disease tend to live longer than men with the same condition.

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Jul 27, 2020

Brain cell types identified that may push males to fight and have sex

Posted by in categories: biotech/medical, neuroscience, sex

Two groups of nerve cells may serve as “on-off switches” for male mating and aggression, suggests a new study in rodents. These neurons appear to send signals between two parts of the brain—the back tip, or posterior, of the amygdala and the hypothalamus—that together regulate emotions including fear, anxiety, and aggression.

Led by researchers at NYU Grossman School of Medicine, the study showed that male mice struggled to have sex in experiments that blocked signals from one cell group that communicates with the hypothalamus (MPN-signaling ). When the same signals were instead bolstered, the animals were not only able to mate but would repeatedly court unreceptive females, something they would not do normally.

Similarly, when the action of a second cell group in the amygdala that also communicates with the hypothalamus (VMHvl-signaling cells) was blocked, the rodents attacked unfamiliar males half as often. When these same neurons were triggered, the mice became unusually aggressive, even attacking their female mates and familiar males.

Jul 24, 2020

A Crispr Cow Is Born. It’s Definitely a Boy

Posted by in categories: biotech/medical, sex

UC Davis scientists spent years editing a sex-determining gene into bovine embryos using Crispr. In April, Cosmo arrived—and his DNA reveals how far the field has to go.

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