Lifeboat Foundation

Scientists at the University of Liverpool have sequenced the genome of the bowhead whale, estimated to live for more than 200 years with low incidence of disease.

Published in the journal Cell Reports, the research could offer new insight into how animals and humans could achieve a long and healthy life.

Scientists compared the genome with those from other shorter-lived mammals to discover genetic differences unique to the bowhead whale.

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Animal products, including meat, cheese, and eggs contain carnitine and choline, metabolites that are converted by gut bacteria into TMA, which is then converted by the liver into TMAO. Plasma levels of TMAO are associated with an increased risk of disease and death, so should we limit intake of these animal products?

Continue reading “Kidney Function: The Missing Link In The TMAO-Health And Disease Story?” »

The motion of magnetic particles as they pass through a magnetic field is called magnetophoresis. Until now, not much was known about the factors influencing these particles and their movement. Now, researchers from the University of Illinois Chicago describe several fundamental processes associated with the motion of magnetic particles through fluids as they are pulled by a magnetic field.

Their findings are reported in the journal Proceedings of the National Academy of Sciences.

Understanding more about the motion of magnetic particles as they pass through a magnetic field has numerous applications, including drug delivery, biosensors, molecular imaging, and catalysis. For example, magnetic nanoparticles loaded with drugs can be delivered to discrete spots in the body after they are injected into the bloodstream or cerebrospinal fluid using magnets. This process currently is used in some forms of chemotherapy for the treatment of cancer.

TEL AVIV — November 18, 2020: In a scientifically verified approach, signalling an important breakthrough in the study of aging, Tel Aviv University and The Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center announced today that, for the first time in humans, two key biological hallmarks of aging, telomere length shortening, and accumulation of senescent cells, can be reversed. The prospective clinical trial, published in peer-reviewed Journal Aging, utilizes Hyperbaric Oxygen Therapy protocols to demonstrate cellular level improvement in healthy aging adults.

For the first-time a human study shows the reversal in the biology of aging including telomere shortening with Hyperbaric Oxygen Therapy.

Continue reading “Hyperbaric Oxygen Therapy: First Human Study Shows Reversal in Biology of Aging” »

Fantastic news for a change!

The ageing process has been biologically reversed for the first time by giving humans oxygen therapy in a pressurised chamber.

Scientists in Israel showed they could turn back the clock in two key areas of the body believed to be responsible for the frailty and ill-health that comes with growing older.

Continue reading “Human ageing process biologically reversed in world first” »

Viruses are tiny invaders that cause a wide range of diseases, from rabies to tomato spotted wilt virus and, most recently, COVID-19 in humans. But viruses can do more than elicit sickness — and not all viruses are tiny.

Large viruses, especially those in the nucleo-cytoplasmic large DNA virus family, can integrate their genome into that of their host — dramatically changing the genetic makeup of that organism. This family of DNA viruses, otherwise known as “giant” viruses, has been known within scientific circles for quite some time, but the extent to which they affect eukaryotic organisms has been shrouded in mystery — until now.

“Viruses play a central role in the evolution of life on Earth. One way that they shape the evolution of cellular life is through a process called endogenization, where they introduce new genomic material into their hosts. When a giant virus endogenizes into the genome of a host algae, it creates an enormous amount of raw material for evolution to work with,” said Frank Aylward, an assistant professor in the Department of Biological Sciences in the Virginia Tech College of Science and an affiliate of the Global Change Center housed in the Fralin Life Sciences Institute.

Continue reading “Lurking in Genomic Shadows: How Giant Viruses Fuel the Genetic Evolution of Organisms” »

Researchers warn that official figures underestimate the pandemic’s real death toll, which could more than triple if the virus is allowed to spread unchecked.

Summary: Study confirms an association between an imbalance in gut bacteria and the development of amyloid plaques in the brains of humans.

Source: University of Geneva

Alzheimer’s disease is the most common cause of dementia. Still incurable, it directly affects nearly one million people in Europe, and indirectly millions of family members as well as society as a whole. In recent years, the scientific community has suspected that the gut microbiota plays a role in the development of the disease.

A researcher from The Australian National University (ANU) has used one of the most powerful supercomputers in the world to predict the quantum mechanical properties of large molecular systems with an accuracy that surpasses all previous experiments.

Calculations of this type have the potential to solve important problems in energy generation, fuel production, water purification, and the manufacturing of medicines, foods, textiles, and consumer goods.

By running his new algorithms on the Summit supercomputer at the Oak Ridge National Lab in the U.S., Dr. Giuseppe Barca has broken the world record for the largest Hartree-Fock calculation ever performed, setting new standards in High-Performance Computing.