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Category: biotech/medical

Simple wipe test reveals hidden PFAS contamination on firefighter protective gear

The flames die down. The sirens fade. Firefighters peel off their gear, thinking the danger has passed. But in the quiet aftermath, another enemy lingers, an invisible film of “forever chemicals” clinging to jackets, pants and masks.

Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have developed a way to see what the eye cannot.

A simple wipe test detected invisible cancer-linked “forever chemicals” on every set of firefighter gear examined, including breathing masks, according to new research from Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine. The non-destructive method offers fire departments a practical way to identify and reduce exposure to per-and polyfluoroalkyl substances (PFAS), chemicals tied to increased cancer risk that can linger on gear long after a fire is out.

High risk of sleep apnea linked to poorer mental health in adults over 45

Researchers at Ottawa Hospital Research Institute and University of Ottawa found that high risk of obstructive sleep apnea was associated with approximately 40% higher odds of a composite poor mental health outcome at baseline and follow-up among adults aged 45–85 years in the Canadian Longitudinal Study on Aging.

Identifying factors associated with mental health outcomes is an important goal on several fronts. Mental health conditions rank among the leading contributors to global disease burden, with anxiety and depressive disorders described as most common. Individuals living with mental health conditions face higher risks of cardiometabolic diseases, unemployment, homelessness, disability, and hospitalizations. Economically, mental disorders carry an estimated $1 trillion annual global cost in lost productivity.

Obstructive sleep apnea (OSA) involves repeated upper airway narrowing during sleep. Disturbed breathing can break up sleep (sleep fragmentation), trigger a stress response in the nervous system (sympathetic activation), and cause episodes of low oxygen in the blood (intermittent hypoxemia).

Too much screen time too soon? Study links infant screen exposure to brain changes and teen anxiety

Children exposed to high levels of screen time before age 2 showed changes in brain development that were linked to slower decision-making and increased anxiety by their teenage years, according to new research by Asst. Prof. Tan Ai Peng and her team from A*STAR Institute for Human Development and Potential (A*STAR IHDP) and National University of Singapore (NUS) Yong Loo Lin School of Medicine, using data from the Growing Up in Singapore Towards Healthy Outcomes (GUSTO) cohort.

New robotic skin lets humanoid robots sense pain and react instantly

If you accidentally put your hand on a hot object, you’ll naturally pull it away fast, before you have to think about it. This happens thanks to sensory nerves in your skin that send a lightning-fast signal to your spinal cord, which immediately activates your muscles. The speed at which this happens helps prevent serious burns. Your brain is only informed once the movement has already started.

If something similar happens to a humanoid robot, it typically has to send sensor data to a central processing unit (CPU), wait for the system to process it, and then send a command to the arm’s actuators to move. Even a brief delay can increase the risk of serious damage.

But as humanoid robots move out of labs and factories and into our homes, hospitals and workplaces, they will need to be more than just pre-programmed machines if they are to live up to their potential. Ideally, they should be able to interact with the environment instinctively. To help make that happen, scientists in China have developed a neuromorphic robotic e-skin (NRE-skin) that gives robots a sense of touch and even an ability to feel pain.

Ethylene and oxygen found to drive periderm regeneration after plant injury

Plants have an extraordinary ability to sense tissue damage and quickly rebuild their protective outer layers, a process vital for survival amid environmental stresses. The periderm—a specialized protective tissue found in many woody plants—serves as a crucial barrier against water loss, pathogens, and mechanical injury. However, understanding how gaseous molecules enable plants to rapidly detect surface disruptions has long remained elusive.

In a new study published in Plant Communications on December 8, a research team led by Prof. Chen Yaning from the Xinjiang Institute of Ecology and Geography (XIEG) of the Chinese Academy of Sciences reported new insights into gas-regulated wound signaling in plants. By examining recent advances in the field, the researchers showed that changes in the diffusion dynamics of ethylene and oxygen within plant tissues provide an efficient and rapid means of sensing breaches in surface defenses.

“When the plant’s outer barrier is damaged, endogenous ethylene gas escapes more readily into the atmosphere (efflux), while oxygen from the environment infiltrates the tissue (influx),” said Dr. Hassan Iqbal, first author of the study.

COVID-19 Leaves Lasting Changes in the Brain, Even After Full Recovery

Summary: Advanced imaging reveals that COVID-19 may cause lasting brain changes, even in people without ongoing symptoms, pointing to hidden neurological effects that could persist long after recovery.

COVID-19 affects more than the lungs. Research shows that even after people have fully recovered from the infection, the virus can cause significant changes in the brain, underscoring its lasting effects on neurological health.

COVID-19 is widely recognized for its impact on the lungs, but growing evidence shows that the virus can also cause lasting changes in the brain, even in people who have fully recovered. These findings point to potential long-term neurological consequences that extend beyond the acute phase of the illness.

A Disrupted Brain Rhythm May Explain Anxiety, Insomnia, and Worse in Cancer Patients

Scientists have discovered that breast cancer can disturb the brain’s daily stress hormone rhythms early in disease development. “The brain is an exquisite sensor of what’s going on in your body,” says Cold Spring Harbor Laboratory Assistant Professor Jeremy Borniger. “But it requires balance. Ne

Pathogenic Variants in Hypertrophic and Dilated Cardiomyopathies

Polygenic scores for hypertrophic and dilated cardiomyopathies independently and oppositely modified disease risk and penetrance of pathogenic variants, supporting bidirectional genetic influences on Cardiomyopathy.

Question How is risk of hypertrophic and dilated cardiomyopathy modified by polygenic background?

Findings In this cross-sectional study including 49 434 individuals in the Penn Medicine BioBank, polygenic scores for hypertrophic and dilated cardiomyopathies were associated with clinical and echocardiographic measures relevant to both diseases and inversely modified the penetrance of pathogenic variants.

Meaning The findings indicate that polygenic background exists on an overlapping, opposing spectrum and may contribute to hypertrophic and dilated cardiomyopathy susceptibility.

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