Archive for the ‘biotech/medical’ category

Jul 20, 2021

Dr. Jean M. Hebert, Ph.D. — Replacing Aging — Albert Einstein College of Medicine

Posted by in categories: bioengineering, biotech/medical, genetics, life extension, neuroscience

Replacing Aging — Dr. Jean M. Hebert, Ph.D. Albert Einstein College of Medicine.

Dr. Jean M. Hebert, Ph.D. (https://einsteinmed.org/faculty/9069/jean-hebert/) is Professor in the Department of Genetics and in the Dominick P. Purpura Department of Neuroscience, at Albert Einstein College of Medicine.

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Jul 20, 2021

The virus trap

Posted by in categories: biotech/medical, genetics, nanotechnology

To date, there are no effective antidotes against most virus infections. An interdisciplinary research team at the Technical University of Munich (TUM) has now developed a new approach: they engulf and neutralize viruses with nano-capsules tailored from genetic material using the DNA origami method. The strategy has already been tested against hepatitis and adeno-associated viruses in cell cultures. It may also prove successful against corona viruses.

Jul 20, 2021

Why identical mutations cause different types of cancer

Posted by in categories: biotech/medical, genetics

“Our studies in mice revealed how genes co-operate to cause cancer in different organs. We identified main players, the order in which they occur during tumor progression, and the molecular processes how they turn normal cells into threatening cancers. Such processes are potential targets for new treatments”.

Why do alterations of certain genes cause cancer only in specific organs of the human body? Scientists at the German Cancer Consortium (DKTK), the Technical University of Munich (TUM), and the University Medical Center Göttingen have now demonstrated that cells originating from different organs are differentially susceptible to activating mutations in cancer drivers: The same mutation in precursor cells of the pancreas or the bile duct leads to fundamental different outcomes. The team discovered for the first time that tissue specific genetic interactions are responsible for the differential susceptibility of the biliary and the pancreatic epithelium towards transformation by oncogenes. The new findings could guide more precise therapeutic decision making in the future.

There have been no major improvements in the treatment of pancreatic and in the last decades and no effective targeted therapies are available to date. “The situation for patients with pancreatic and extrahepatic bile duct cancer is still very depressing with approximately only 10% of patients surviving five years,” says Dieter Saur, DKTK Professor for Translational Cancer Research at TUM’s university hospital Klinikum rechts der Isar, DKTK partner site Munich.

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Jul 20, 2021

New universal coronavirus vaccine could prevent future pandemics

Posted by in categories: biotech/medical, health

CHAPEL HILL, N.C. – Scientists at the University of North Carolina Gillings School of Global Public Health have developed a vaccine that could be effective against COVID-19, its variants — and a future coronavirus pandemic.

While no one knows which virus may cause the next outbreak, coronaviruses remain a threat after causing the SARS outbreak in 2003 and the global COVID-19 pandemic.

According to a study published June 22 in Science, the vaccine designed at UNC-Chapel Hill protected mice from the current SARS-CoV-2 coronavirus, plus a group of coronaviruses known to make the jump from animals to humans.

Jul 20, 2021

First universal coronavirus vaccine will start human trials this year

Posted by in category: biotech/medical

The world is in urgent need of a vaccine that protects against all coronaviruses, even those we’ve not met yet, warn scientists, as plans for human trials of potential candidates ramp up.

Jul 20, 2021

$25 Million Raised for SENS Antiaging Research Via Pulsechain Crypto Drive

Posted by in categories: biotech/medical, bitcoin, cryptocurrencies, life extension

Pulsechain has raised $25000, 000 for antiaging medical research after 5 days of a 14 day fundraiser. You must follow the SENS.org PulseChain instructions. Sacrifices to SENS.org during the sacrifice phase earn 25% less points compared to sacrifices at Pulse.info. SENS.org can also accept stocks and bank wires. Once the sacrifice phase is over, the total sacrifice points for each sacrificer’s address’s points (at the same metamask address) are totaled up across all the supported chains and the SENS.org report. This creates a list of sacrificers ranked by total points from largest to smallest.

SENS Research Foundation has been working to develop, promote, and ensure widespread access to therapies that cure and prevent the diseases and disabilities of aging by comprehensively repairing the damage that builds up in our bodies over time. SENS is redefining the way the world researches and treats age-related ill health, while inspiring the next generation of biomedical scientists. Aubrey dr Grey and SENS have been the leading proponents of repairing aging damage to reverse aging effects. They have been leading the research effort for aging damage repair for over 20 years.

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Jul 20, 2021

Chemists Found an Effective Remedy for “Aged” Brain Diseases

Posted by in categories: biotech/medical, chemistry, neuroscience

Summary: Newly synthesized compounds can halt the degradation of neurons in a range of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, researchers say.

Source: Ural Federal University

Russian scientists have synthesized chemical compounds that can stop the degeneration of neurons in Alzheimer’s, Parkinson’s, and other severe brain pathologies. These substances can provide a breakthrough in the treatment of neurodegenerative pathologies.

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Jul 20, 2021

Non-Neuronal Cells Drive Sex Differences in Early Brain Development

Posted by in categories: biotech/medical, neuroscience, sex

“In this study, for the first time, we see evidence that events which were always assumed to be occurring in the same manner, regardless of sex, may actually be completely different in males compared to females. The fact that these differences involve astrocytes, which have traditionally been ignored in neuroscience but have recently become a hot topic for study, makes them all the more intriguing.”

Summary: Thrombospondin-2, a protein with cell adhesion properties usually secreted by astrocytes, prompted a strong increase in synapses in male-derived neurons but showed no effect in females.

Source: Marshall University

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Jul 20, 2021

Researchers Find Common Denominator Linking All Cancers

Posted by in categories: biotech/medical, health

All cancers fall into just two categories, according to new research from scientists at Sinai Health, in findings that could provide a new strategy for treating the most aggressive and untreatable forms of the disease.

In new research out this month in Cancer Cell, scientists at the Lunenfeld-Tanenbaum Research Institute (LTRI), part of Sinai Health, divide all cancers into two groups, based on the presence or absence of a protein called the Yes-associated protein, or YAP.

Rod Bremner, senior scientist at the LTRI, said they have determined that all cancers are present with YAP either on or off, and each classification exhibits different drug sensitivities or resistance. YAP plays an important role in the formation of malignant tumours because it is an important regulator and effector of the Hippo signaling pathway.

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Jul 20, 2021

Transforming Brain Waves into Words with AI

Posted by in categories: biotech/medical, robotics/AI

New research out of the University of California, San Francisco has given a paralyzed man the ability to communicate by translating his brain signals into computer generated writing. The study, published in The New England Journal of Medicine, marks a significant milestone toward restoring communication for people who have lost the ability to speak.

“To our knowledge, this is the first successful demonstration of direct decoding of full words from the brain activity of someone who is paralyzed and cannot speak,” senior author and the Joan and Sanford Weill Chair of Neurological Surgery at UCSF, Edward Chang said in a press release. “It shows strong promise to restore communication by tapping into the brain’s natural speech machinery.”

Some with speech limitations use assistive devices–such as touchscreens, keyboards, or speech-generating computers to communicate. However, every year thousands lose their speech ability from paralysis or brain damage, leaving them unable to use assistive technologies.

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