Specialized squid tissues contain refractive proteins called reflectins, which help the animal evade detection and offer potential bioengineering applications.
Category: bioengineering
Human Cyborgs Are No Longer Science Fiction! (Insane Breakthroughs)
Are human cyborgs the future? You won’t believe how close we are to merging humans with machines! This video uncovers groundbreaking advancements in cyborg technology, from bionic limbs and brain-computer interfaces to biological robots like anthrobots and exoskeletons. Discover how these innovations are reshaping healthcare, military, and even space exploration.
Learn about real-world examples, like Neil Harbisson, the colorblind cyborg artist, and the latest developments in brain-on-a-chip technology, combining human cells with artificial intelligence. Explore how cyborg soldiers could revolutionize the battlefield and how genetic engineering might complement robotic enhancements.
The future of human augmentation is here. Could we be on the verge of transforming humanity itself? Dive in to find out how science fiction is quickly becoming reality.
How do human cyborgs work? What are the latest AI breakthroughs in cyborg technology? How are cyborgs being used today? Could humans evolve into hybrid beings? This video answers all your questions. Don’t miss it!
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Engineering biology applications for environmental solutions: potential and challenges
Engineering biology applies synthetic biology to address global environmental challenges like bioremediation, biosequestration, pollutant monitoring, and resource recovery. This perspective outlines innovations in engineering biology, its integration with other technologies (e.g., nanotechnology, IoT, AI), and commercial ventures leveraging these advancements. We also discuss commercialisation and scaling challenges, biosafety and biosecurity considerations including biocontainment strategies, social and political dimensions, and governance issues that must be addressed for successful real-world implementation. Finally, we highlight future perspectives and propose strategies to overcome existing hurdles, aiming to accelerate the adoption of engineering biology for environmental solutions.
The scale of global environmental challenges requires a multi-pronged approach, which utilises all the technologies at our disposal. Here, authors provide their perspective on the potential of engineering biology for environmental biotechnology, summarizing their thoughts on the key challenges and future possibilities for the field.
Engineers turn toxic ancient tomb fungus into anti-cancer drug
Penn-led researchers have turned a deadly fungus into a potent cancer-fighting compound. After isolating a new class of molecules from Aspergillus flavus, a toxic crop fungus linked to deaths in the excavations of ancient tombs, the researchers modified the chemicals and tested them against leukemia cells. The result? A promising cancer-killing compound that rivals FDA-approved drugs and opens up new frontiers in the discovery of more fungal medicines.
“Fungi gave us penicillin,” says Sherry Gao, Presidential Penn Compact Associate Professor in Chemical and Biomolecular Engineering (CBE) and in Bioengineering (BE) and senior author of a new paper in Nature Chemical Biology on the findings. “These results show that many more medicines derived from natural products remain to be found.”
Latest Trends in Artificial Intelligence in Biotechnology & Biology
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Creating the World’s First CRISPR Medicine, for Sickle Cell Disease
When Vijay Sankaran was an MD-PhD student at Harvard Medical School in the mid-2000s, one of his first clinical encounters was with a 24-year-old patient whose sickle cell disease left them with almost weekly pain episodes.
“The encounter made me wonder, couldn’t we do more for these patients?” said Sankaran, who is now the HMS Jan Ellen Paradise, MD Professor of Pediatrics at Boston Children’s Hospital.
In 2008, Orkin, Sankaran, and colleagues achieved their vision by identifying a new therapeutic target for sickle cell disease.
In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long endeavor reached fruition in the form of a new treatment, CASGEVY, approved by the U.S. Food and Drug Administration.
The decision has ushered in a new era for sickle cell disease treatment — and marked the world’s first approval of a medicine based on CRISPR/Cas9 gene-editing technology.
How a genetic insight paired with gene editing technology led to a life-changing new therapy.
Gene-editing nanoparticle system targets multiple organs simultaneously
A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a new study shows. The findings, published in Nature Biotechnology, could lead to new therapies for a variety of genetic diseases that affect multiple organs.
“Multi-organ diseases may need to be treated in more than one place. The development of multi-organ-targeted therapeutics opens the door to realizing those opportunities for this and other diseases,” said study leader Daniel Siegwart, Ph.D., Professor of Biomedical Engineering, Biochemistry, and in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern.
Gene editing—a group of technologies designed to correct disease-causing mutations in the genome—has the potential to revolutionize medicine, Dr. Siegwart explained. Targeting these technologies to specific organs, tissues, or cell populations will be necessary to effectively and safely treat patients.
Years of painting restoration work done in just hours by new technique
Although AI-based restoration methods can indeed bring new life to damaged paintings, the end result is typically a digital copy of the original painting. By contrast, a new MIT technique applies reversible repairs to the physical painting itself, in the form of a removable mask.
The process was developed by mechanical engineering graduate student Alex Kachkine, who restores paintings via traditional hand-painting techniques as a hobby.
He realized that many galleries have a number of paintings which never get displayed, because they require restoration that would take too long – and thus be too expensive – to perform by hand. Utilizing his method, however, restoration times could be reduced from years, months or weeks down to a matter of hours.
Quantum computing tackles classical fluid dynamics challenges
Researchers at the Department of Energy’s Oak Ridge National Laboratory have tested a quantum computing approach to an old challenge: solving classical fluid dynamics problems.
The work is published in the journal Physics of Fluids. The results highlight avenues for further study of quantum computing’s potential to aid scientific discovery.
For the test problem, the research team used the Hele-Shaw flow problem—a scenario of two flat, parallel plates extremely close to each other and the flow of liquids and gases between them. The problem, although idealized, offers important applications in real-world problems such as microfluidics, groundwater flow, porous media flow, oil recovery and bioengineering.
