The new gaming dimension is here. The Odyssey 3D brings stunning glasses-free 3D experience to life – making games feel more real and the action more exciting. Discover more at http://www.samsung.com.
• Glasses-free 3D experience. • AI 3D Video Conversion. • 165Hz refresh rate and 1ms response time (GtG) • Nvidia G-Sync Compatible.
Our cells rely on microscopic highways and specialized protein vehicles to move everything—from positioning organelles to carting protein instructions to disposing of cellular garbage. These highways (called microtubules) and vehicles (called motor proteins) are indispensable to cellular function and survival.
The dysfunction of motor proteins and their associated proteins can lead to severe neurodevelopmental and neurodegenerative disorders. For example, the dysfunction of Lis1, a partner protein to the motor protein dynein, can lead to the rare fatal birth defect lissencephaly, or “smooth brain,” for which there is no cure. But therapeutics that target and restore dynein or Lis1 function could change those dismal outcomes—and developing those therapeutics depends on thoroughly understanding how dynein and Lis1 interact.
New research from the Salk Institute and UC San Diego captured short movies of Lis1 “turning on” dynein. The movies allowed the team to catalog 16 shapes that the two proteins take as they interact, some of which have never been seen before. These insights will be foundational for designing future therapeutics that restore dynein and Lis1 function, since they shine a light on precise locations where drugs could interact with the proteins.
A new camera setup can record three-dimensional movies with a single pixel. Moreover, the technique can obtain images outside the visible spectrum and even through tissues. The Kobe University development thus opens the door to holographic video microscopy.
Holograms are not only used as fun-to-look-at safety stickers on credit cards, electronic products or banknotes; they have scientific applications in sensors and in microscopy as well. Traditionally, holograms require a laser for recording, but more recently, techniques that can record holograms with ambient light or light emanating from a sample have been developed.
There are two main techniques that can achieve this: one is called “FINCH” and uses a 2D image sensor that is fast enough to record movies, but is limited to visible light and an unobstructed view, while the other is called “OSH,” which uses a one-pixel sensor and can record through scattering media and with light outside the visual spectrum, but can only practically record images of motionless objects.