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Dec 23, 2016

Positive multiple sclerosis clinical trial suggests ‘unprecedented’ effects in relapsing form of the disease

Posted by in category: biotech/medical

More progress in treating MS.


In findings that show the effectiveness of a new strategy for treating multiple sclerosis (MS), researchers are reporting positive results from three large, international, multicenter Phase III clinical trials of the investigational drug ocrelizumab (brand name Ocrevus) in both relapsing multiple sclerosis (RMS) and primary progressive multiple sclerosis (PPMS).

The trial results are published online on Dec. 21, 2016, in The New England Journal of Medicine (NEJM), and are discussed in an accompanying editorial.

In , the immune system attacks the body, making it a so-called autoimmune disease. To date, all MS drugs have targeted the immune system’s T cells. Ocrelizumab, in contrast, depletes populations of the immune system’s B cells.

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