Researchers in Cambridge have created a new approach for creating and transplanting artificial bile ducts with the aim of treating liver disease in children and reducing the need for transplants.
The research, published in the journal Nature Medicine, shows how the researchers grew 3D cell structures and transplanted them into mice[1]. These structures then developed into functional bile ducts.
The bile ducts are long, tubular structures that carry bile secreted by the liver which is critical for helping us to digest our food. When these ducts do not function properly, such as in childhood diseases like biliary atresia, it can lead to a damaging buildup of bile in the liver.
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