Lifeboat Foundation

New Whitehead Institute research may prove to be a useful paradigm for targeting diseases caused by abnormal methylation. Credit: Steven Lee/Whitehead Institute Fragile X syndrome is the most frequent cause of intellectual disability in males, affecting one out of every 3,600 boys born. The syndrome can also cause autistic traits, such as social and communication deficits, as well as attention problems and hyperactivity. Currently, there is no cure for this disorder. Fragile X syndrome is caused by mutations in the FMR1 gene on the X chromosome, which prevent the gene’s expression. This abs…