Page 13
Jan 29, 2019
Drug compound could be next-generation treatment for aggressive form of leukemia
Posted by Paul Battista in category: biotech/medical
Researchers have been struggling for years to find a treatment for patients who have a recurrence of acute myeloid leukemia (AML), an aggressive blood cancer that is one of the most lethal cancers. About 19,520 news cases are diagnosed a year, and about 10,670 people a year die from it, according to the American Cancer Society.
Purdue University researchers are developing a series of drug compounds that have shown promise in treating such cases. About 30 percent of AML patients have a mutation caused by a kinase called FLT3, which makes the leukemia more aggressive. Inhibitors of FLT3, such as Radapt, approved last year by the U.S. Food and Drug Administration, have shown good initial response to treating leukemia. Gilteritinib, another FLT3 inhibitor, was recently approved toward the end of 2018. But AML patients on FLT3 inhibitor therapy often relapse because of secondary mutations in the FLT3 and existing treatments have not been fully successful in treating those cases.
Researchers on a team led by Herman O. Sintim, the Drug Discovery Professor of Chemistry in Purdue’s Department of Chemistry, say they have developed a series of compounds that work not only on AML with common FLT3 mutation, but also drug-resistant AML harboring problematic mutations, such as the gatekeeper F691L mutation, which some leukemia patients who relapse harbor.
Jan 29, 2019
Soon we’ll cure diseases with a cell, not a pill
Posted by Paul Battista in categories: biotech/medical, futurism
Current medical treatment boils down to six words: Have disease, take pill, kill something. But physician Siddhartha Mukherjee points to a future of medicine that will transform the way we heal.
Jan 29, 2019
Scientists Generate Quantum Entanglement in Space For the First Time
Posted by Paul Battista in categories: quantum physics, space
The entangled photons were beamed to three ground stations across China, each separated by more than 700 miles—a new record.
Jan 29, 2019
Clinton Township, MI
Posted by Paul Battista in categories: biotech/medical, cryonics, education, life extension
We specialize in the cryo-preservation of humans and pets, DNA & tissue storage as well as cryonics outreach and public education.
Jan 29, 2019
Alzheimer’s blood test detects brain damage years before symptoms
Posted by Paul Battista in categories: biotech/medical, neuroscience
Testing blood levels of a protein that brain cells leak when faulty or dying detected people with Alzheimer’s disease years before their symptoms emerged.
Jan 29, 2019
Can AI help crack the code of fusion power?
Posted by Klaus Baldauf in category: robotics/AI
Jan 29, 2019
Engineers translate brain signals directly into speech
Posted by Caycee Dee Neely in categories: innovation, robotics/AI
History Made
In a scientific first, Columbia neuroengineers have created a system that translates thought into intelligible, recognizable speech. By monitoring someone’s brain activity, the technology can reconstruct the words a person hears with unprecedented clarity. This breakthrough, which harnesses the power of speech synthesizers and artificial intelligence, could lead to new ways for computers to communicate directly with the brain. It also lays the groundwork for helping people who cannot speak, such as those living with as amyotrophic lateral sclerosis (ALS) or recovering from stroke, regain their ability to communicate with the outside world.
Jan 29, 2019
As tropical oceans warm, we could see a substantial increase in extreme rain storms
Posted by Michael Lance in category: climatology
A new study led by the NASA Jet Propulsion Laboratory finds that 21 percent more storms will form for every 1.8° F (1° C) that ocean surface temperatures rise. See the projections based on currently accepted climate models: https://go.nasa.gov/2GcAS65
Jan 29, 2019
Mayhem, the Machine That Finds Software Vulnerabilities, Then Patches Them
Posted by Caycee Dee Neely in categories: business, cybercrime/malcode, robotics/AI
Bug and vulnerability hunting is a big business and the need for it is getting larger and larger. Up until this point, the majority of work had been from people. Either as hackers discovered holes and released exploits or as companies paid people to do the testing.
The machine triumphed in DARPA’s Cyber Grand Challenge, where teams automated white-hat hacking.