CRISPR/Cas9 is a form of genetic editing that holds a lot of promise, such as the killing of cancer cells, but also comes with some hefty warnings, such as that it may cause DNA damage. So far, scientists have been using CRISPR/Cas9 in a variety of plants and animals to edit genetic information, including attempts to practice what is called ‘active genetics’.
This last approach is an attempt to edit the genome that controls which of the two copies of a gene is passed to the next generation. But the technique is complicated and rife with obstacles so thus far been used only on insects. Not anymore!
A team of biologists has now achieved the world’s first CRISPR/Cas9-based approach to control genetic inheritance in a mammal.
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