Scientists at the University of Helsinki working in collaboration with the University of Oxford have deciphered for the first time how a virus genome is condensed inside the capsid of a virus.
“The motivation of the study was to increase our basic understanding of viral replication, but in the long term this may contribute to tackling viral disease,” says the director of the of the project, Associate Professor Juha Huiskonen from the Helsinki Institute of Life Science, HiLIFE.
The breakthrough results were achieved using cryogenic electron microscopy, a method that has in recent years revolutionised structural biology—a field of biology that aims to understand how molecules of life work at the atomic level.
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