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May 30, 2021

High FGF21, Low Insulin And Glucose: A Pro-Longevity Strategy?

Posted by in categories: biotech/medical, life extension

Papers referenced in the video:

FGF21 and Chronic Kidney Disease: https://www.sciencedirect.com/science/article/pii/S002604952100038X

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466591/

Inhibition of growth hormone signaling by the fasting-induced hormone FGF21:
https://pubmed.ncbi.nlm.nih.gov/18585098/

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice:
https://pubmed.ncbi.nlm.nih.gov/32877690/

Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression:
https://pubmed.ncbi.nlm.nih.gov/31773901/

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