Jul 7, 2021

Rejuvenating Mouse Brains With Ketamine or Flickering Light

Posted by in categories: life extension, neuroscience


Summary: Ketamine and exposure to 60-hertz flickering light show promise as a potentially new, non-invasive therapy to help rejuvenate the aging brain.

Source: IST Austria

Can you remember the smell of flowers in your grandmother’s garden or the tune your grandpa always used to whistle? Some childhood memories are seemingly ingrained into your brain. In fact, there are critical periods in which the brain learns and saves profound cognitive routines and memories. The structure responsible for saving them is called the perineuronal net.

This extracellular structure envelops certain neurons, thereby stabilizes existing connections – the synapses – between them and prevents new ones from forming. But what if we could remove the perineuronal net and restore the adaptability of a young brain? The neuroscientist Sandra Siegert and her research group at IST Austria now published two promising techniques to do so.

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