Scientists at the Max Planck Institute for the Science of Light (MPL) and Max-Planck-Zentrum für Physik und Medizin (MPZPM) in Erlangen present a large step forward in the characterization of nanoparticles. They used a special microscopy method based on interfereometry to outperform existing instruments. One possible application of this technique may be to identify illnesses.
Nanoparticles are everywhere. They are in our body as protein aggregates, lipid vesicles, or viruses. They are in our drinking water in the form of impurities. They are in the air we breath as pollutants. At the same time, many drugs are based on the delivery of nanoparticles, including the vaccines we have recently been given. Keeping with the pandemics, quick tests used for the detection the SARS-Cov-2 are based on nanoparticles too. The red line, which we monitor day by day, contains myriads of gold nanoparticles coated with antibodies against proteins that report infection.
Technically, one calls something a nanoparticle when its size (diameter) is smaller than one micrometer. Objects of the order of one micrometer can still be measured in a normal microscope, but particles that are much smaller, say smaller than 0.2 micrometers, become exceedingly difficult to measure or characterize. Interestingly, this is also the size range of viruses, which can become as small as 0.02 micrometers.
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