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Aug 23, 2022

In a week, we can tell if something slows aging

Posted by in categories: biotech/medical, life extension, robotics/AI

The early-stage development of many age-targeting compounds often involves studies of their effects on the lifespan of the transparent nematode (worm) model Caenorhabditis elegans. A highly manual process, this exercise is time-consuming and only produces data on one endpoint – lifespan.

Durham University associate professors David Weinkove and Chris Saunter invented a technology that automates measurements of movement in many large populations of worms simultaneously. Crucially, this technology goes beyond measuring lifespan, also capturing information about how worms’ health declines as they age – their healthspan.

Longevity. Technology: Together, Weinkove and Saunter have co-founded a spinout company called Magnitude Biosciences, leveraging their innovative platform to test drugs and other interventions for their capacity to prolong healthspan. We caught up with Weinkove to learn more about the background to the company and where it goes from here.

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