Sep 27, 2022

Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis

Posted by in category: biotech/medical

How do single cells know when and where to proliferate, survive, and die during organ morphogenesis? Ender et al. show how self-organized ERK activity pulses and waves spatiotemporally regulate these fate decisions in a prototype 3D mammary epithelial model.

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