Aging is a complex process that can lead to chronic diseases such as diabetes, cardiovascular disorders, muscular degeneration, atherosclerosis and neurodegeneration, and it is currently one of the major scientific concerns in the field of medicine [1].
Several strategies have been developed to date for the promotion of healthy aging and an increase in the duration of life. One of the recent strategies that can decrease the deleterious impact of aging and increase the regenerative property at the cellular level is cellular reprogramming.
Cellular reprogramming can convert a somatic cell into an induced pluripotent stem cell (iPSC). It not only helps to restore tissue and organ function but also helps to determine cell fate. This, in turn, helps in the maintenance of cellular identity through the expression of cell type-specific genes and suppression of lineage-inappropriate genes [2].
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