Coronaviruses have brought about three massive outbreaks in the past two decades. Each step of its life cycle invariably depends on the interactions among virus and host molecules. The interaction between virus RNA and host protein (IVRHP) is unique compared to other virus-host molecular interactions, and has emerged to be a very hot topic in recent studies.
These studies provide essential information for a deeper understanding of IVRHP, which represents not only an attempt by viruses to promote their translation/replication, but also the host’s endeavor to combat viral pathogenicity. In other words, there is an urgent need to have a panorama of coronavirus RNA-Host protein interactions, which will then aid in the discovery of new antiviral therapies.
On October 6, 2022, Prof. Zhu Feng from College of Pharmaceutical Sciences in Zhejiang University, Prof. Han Lianyi from College of Life Sciences in Fudan University and Prof. Lin Tao from College of Pharmaceutical Sciences in Hangzhou Normal University published an article titled “CovInter: Interaction Data between Coronavirus RNAs and Host Proteins” in Nucleic Acids Research.
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