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Dec 13, 2022

MIT engineers design a soft, implantable ventilator

Posted by in category: biotech/medical

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For many of us, the act of breathing comes naturally. Behind the scenes, our diaphragm — the dome-shaped muscle that lies just beneath the ribcage — works like a slow and steady trampoline, pushing down to create a vacuum for the lungs to expand and draw air in, then relaxing as air is pushed out. In this way, the diaphragm automatically controls our lung capacity, and is the major muscle responsible for our ability to breathe.

But when the diaphragm’s function is compromised, the breathing instinct becomes a laborious task. Chronic diaphragm dysfunction can occur in people with ALS, muscular dystrophy, and other neuromuscular diseases, as well as patients with paralysis, and damage to the phrenic nerve, which stimulates the diaphragm to contract.

A new proof-of-concept design by MIT engineers aims to one day boost the diaphragm’s life-sustaining function and improve lung capacity for people with diaphragm dysfunction.

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