Many of the proteins that play a crucial role in living cells adhere to a core principle of biology: their form, or shape, fits their function. But there is also a vast number of proteins and their parts that defy that dogma.
Why it matters: New findings are revealing how these flexible, disordered proteins work — and deciphering their role in human diseases and potential treatments.
How it works: Whether many medicines, immune cells, or the moment-to-moment inner workings of cells function depends on the shape of proteins they interact with or use.
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