Summary: Researchers have innovated a method to produce lab-grown mini brains, known as human brain organoids, free of animal cells, promising a more accurate study and treatment of neurodegenerative conditions.
Previously, brain organoids were grown using a substance derived from mouse sarcomas called Matrigel, leading to inconsistencies due to its undefined composition and variability. The new method uses an engineered extracellular matrix free of animal components, improving the neurogenesis of brain organoids.
This breakthrough allows for more accurate replication of human brain conditions and could open doors for personalized treatment of neurodegenerative diseases such as ALS and Alzheimer’s.
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