Aug 28, 2023

Naked mole rat ‘longevity gene’ extends lifespan in mice

Posted by in categories: biotech/medical, life extension

Researchers at the University of Rochester have successfully exported a longevity gene from naked mole rats to mice – a transfer that resulted in both improved health and an extension of the mouse’s lifespan [1].

Longevity. Technology: Naked mole rats, which are known for their long lifespans and exceptional resistance to age-related diseases, have been a focus of longevity research for some time. By introducing a specific gene responsible for improved cellular repair and protection into mice, the Rochester researchers have created promising opportunities to better understand the mechanisms behind aging and potentially increase human lifespan.

“Our study provides a proof of principle that unique longevity mechanisms that evolved in long-lived mammalian species can be exported to improve the lifespans of other mammals,” says Vera Gorbunova, the Doris Johns Cherry Professor of biology and medicine at Rochester [2].

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