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The mechanisms of triptan using metabolomics and transcriptomics in spontaneous migraine attacks

Posted in futurism

Migraines are characterized by moderate to severe headache attacks and are commonly considered polygenic disorders. Typically, migraines are treated with triptans like serotonin receptor agonists; however, the mechanisms of triptans are debated upon, with these agents only effective in only about 60% of the population.

A new Scientific Reports study discusses the mechanisms of triptans for the treatment of spontaneous migraine attacks by using transcriptomics and metabolomics.