Nov 25, 2023

New human gene cluster sequence discovered

Posted by in categories: biotech/medical, chemistry, evolution, genetics

Investigators from the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a new repeat gene cluster sequence that is exclusively expressed in humans and non-human primates.

The discovery, detailed in a study published in Science Advances, is a breakthrough for biology and has wide-ranging implications for future research in , , and the study of repetitive DNA sequences, according to the authors.

“This is an unbelievable discovery of the first elongation factor that is repeated within the genome and is very primate-specific,” said Shilatifard, who is also director of the Simpson Querrey Institute for Epigenetics and a professor of Pediatrics.

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