In particular I like the 3D modeling segment.
Here Dr Seranova talks about stem cell use in helping with research into diseases of aging, particularly generating organiods of the brain by growing them from stem cells.
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Dr. Seranova is a serial entrepreneur, holds an MSc in Translational Neuroscience from the University of Sheffield and a PhD in Stem Cell Biology and Autophagy from the University of Birmingham, UK.
⏲️Chapters.
00:00 Clinical trials success rate.
02:10 Aging as a disease.
03:15 Why do clinical trials fail.
05:00 Using stem cells in 3D
09:00 Efficiency of research.
11:45 Organoid formation.
🌐Links in this video.
NMN Bio website: https://nmnbio.co.uk/
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.
https://www.sciencedirect.com/science/article/pii/S2211124723003832
Autophagy promotes cell survival by maintaining NAD levels.
https://pubmed.ncbi.nlm.nih.gov/36413951/
Nicotinamide mononucleotide improves the Alzheimer’s disease by regulating intestinal microbiota.
https://sciencedirect.com/science/article/abs/pii/S0006291X23006538
Nicotinamide mononucleotide inhibits JNK activation to reverse Alzheimer disease.
https://pubmed.ncbi.nlm.nih.gov/28330719/
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