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Mar 26, 2024

From autism to Alzheimer’s: A large-scale animal study links brain pH changes to wide-ranging cognitive issues

Posted by in categories: biotech/medical, neuroscience

A global collaborative research group comprising 131 researchers from 105 laboratories across seven countries has published a paper in eLife. The study identifies brain energy metabolism dysfunction leading to altered pH and lactate levels as common hallmarks in numerous animal models of neuropsychiatric and neurodegenerative disorders, such as intellectual disability, autism spectrum disorders, schizophrenia, bipolar disorder, depressive disorders, and Alzheimer’s disease.

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