Summary: A new study uncovered how epigenetic marks and the Cux2 protein influence brain folding. The study reveals that the epigenetic mark H3K27ac and Cux2 are key to forming the cerebral cortex’s gyri and sulci.
These findings enhance our understanding of brain development and could inform treatments for brain malformations. The research underscores the complexity of the nervous system and the pivotal role of epigenetics in brain structure.
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