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Jun 9, 2024

Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex

Posted by in categories: biotech/medical, neuroscience

Year 2022 This can lead to even greater understanding of the human brain with organiods in mice.


Neuron al organoids derived from human induced pluripotent stem cells can be transplanted and integrated into the rodent cortex for the study of brain development and function. Here the authors demonstrate use of transparent graphene microelectrodes and two photon imaging for longitudinal, multimodal monitoring of functional connectivity between human iPSC derived neuronal organoids and the mouse cortex.

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