Scientists from Nagoya University in Japan have identified the role of serotonin neurons in linking glucose availability to reproductive health. Their research demonstrates how elevated glucose levels stimulate serotonergic neurons, leading to the release of serotonin, which in turn activates kisspeptin neurons responsible for reproductive hormone release. These findings explain why poor nutrition affects fertility and suggest potential treatments for depression-induced infertility through the use of selective serotonin reuptake inhibitors (SSRIs). Credit: SciTechDaily.com.
Scientists from Nagoya University in Japan have clarified the connection between energy levels and fertility in both animals and humans. They discovered that signaling from serotonin neurons plays a crucial role in maintaining reproductive function by detecting glucose availability, which in turn enhances the release of the reproductive hormone gonadotropin. These findings also offer an explanation for the reduced fertility seen in individuals with depression and suggest potential treatments. The study was published in Scientific Reports.
People who lack sufficient nutrition encounter problems with their reproductive health. For example, ballet dancers can experience menstrual disruptions, and women who fast can struggle to conceive. According to a new study led by Designated Associate Professor Sho Nakamura and Professors Hiroko Tsukamura and Satoshi Ohkura, one of the main factors that affect a person’s reproductive health is glucose availability.
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