Research that began with a patient-driven discovery in the lab of YSM’s Carrie Lucas, PhD, could help in fighting autoimmune diseases.
Writing in Nature Immunology, Lucas and colleagues identify a signaling molecule found in immune cells that could be a target for future treatments.
A medical mystery served as the genesis for a Yale-led study that has promising implications for treating a range of autoimmune diseases.
A young girl entered the clinic suffering from blood cell abnormalities, difficulty breathing, and later, diarrhea. She also had been diagnosed with recurrent infections due to low levels of antibody production. Her doctors treated her with corticosteroids to reduce her lung and gut inflammation and immunoglobulin replacement therapy to restore her antibody levels.
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