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Sep 29, 2024

Light-controlled bioassays could diagnose diseases more easily and cost effectively

Posted by in category: biotech/medical

These OptoAssays allow for the bidirectional, light-induced movement of biomolecules and the reading of test results without the need for additional mechanical washing steps.

An OptoAssay uses a sender and a receiver area, which are brought into contact by adding the test reagent. In the sender area, there is a special protein that reacts to light. This protein can either bind or release specific molecules, depending on the type of light it captures.

When an LED emits at a wavelength of 660 nanometers, the molecules bind to the protein. Upon switching to far-red light with a wavelength of 740 nanometers, the molecules detach from the protein. In the receiver area, there are antibodies specifically designed to recognize and capture the target protein in the test reagent.

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