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📝 The Many Faces of Immune Activation in HIV-1 Infection: A Multifactorial Interconnection — Mazzuti, et al.
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Ovarian cancer (OC) is the leading cause of death from gynecological malignancies. Despite great advances in treatment strategies, therapeutic resistance and the gap between preclinical data and actual clinical efficacy justify the necessity of developing novel models for investigating OC. Organoids represent revolutionary three-dimensional cell culture models, deriving from stem cells and reflecting the primary tissue’s biology and pathology. The aim of the current review is to study the current status of mouse-and patient-derived organoids, as well as their potential to model carcinogenesis and perform drug screenings for OC.
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