Using an innovative approach, EMBL scientists uncovered key interactions between molecular machines, potentially opening new avenues for drug development.
Choosing a film for a movie night is always a battle. Now imagine if you could pick one that provided a window into some of the most fundamental biological processes that keep us alive. For the first time ever, researchers have captured a real-time molecular movie to show how two essential cellular processes – transcription and translation – interact with each other in bacteria.
In all living organisms, DNA contains the code that defines cellular structures and functions. An enzyme called RNA polymerase deciphers this code and converts it into RNA, a molecule that closely resembles DNA. This transfer of life’s code from DNA to RNA is called transcription. Next, a molecular machine called ‘ribosome’ uses the message encoded in RNA to build proteins – the molecules performing most of the essential functions of our cells. This process is called translation.
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