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#bioink could be used to #Print and #Grow #Lung #Tissue.

Researchers describe their success in creating a mucus-based bioink for 3D printing lung tissue. This advancement could one day help study and treat chronic lung conditions. scitechupdates.com/mucus-based-bi


Lung diseases kill millions of people around the world each year. Treatment options are limited, and animal models for studying these illnesses and experimental medications are inadequate. Now, writing in ACS Applied Bio Materials, researchers describe their success in creating a mucus-based bioink for 3D printing lung tissue. This advancement could one day help study and treat chronic lung conditions.

While some people with lung diseases receive transplants, donor organs remain in short supply. As an alternative, medications and other treatments can be used to manage symptoms, but no cure is available for disorders such as chronic obstructive pulmonary disease and cystic fibrosis. Researchers continue to seek better medications, often relying on testing in rodents. But these animal models may only partially capture the complexities of pulmonary diseases in humans, and they might not accurately predict the safety and efficacy of new drugs.

The widespread adoption of electric vehicles greatly relies on the development of robust and fast-charging battery technologies that can support their continuous operation for long periods of time. One proposed energy storage solution to improve the endurance of electric vehicles entails the use of so-called structural batteries.

Structural batteries are batteries that can serve two purposes, acting both as structural components of vehicles and solutions. Instead of being external components that are added to an electronic or electric device, these batteries are thus directly embedded into the structure.

Researchers at Shanghai University and their collaborators recently devised a promising strategy to fabricate highly performing structural batteries with customizable geometric configurations. Their strategy, outlined in a paper published in Composites Science and Technology, enables the 3D-printing of structural lithium-ion batteries for different geometrical configurations.

Researchers from North Carolina State University have demonstrated miniature soft hydraulic actuators that can be used to control the deformation and motion of soft robots that are less than a millimeter thick. The researchers have also demonstrated that this technique works with shape memory materials, allowing users to repeatedly lock the soft robots into a desired shape and return to the original shape as needed.

“Soft robotics holds promise for many applications, but it is challenging to design the actuators that drive the motion of soft robots on a small scale,” says Jie Yin, corresponding author of a paper on the work (Advanced Materials, “Fully 3D-Printed Miniature Soft Hydraulic Actuators with Shape Memory Effect for Morphing and Manipulation”) and an associate professor of mechanical and aerospace engineering at NC State. “Our approach makes use of commercially available multi-material 3D printing technologies and shape memory polymers to create soft actuators on a microscale that allow us to control very small soft robots, which allows for exceptional control and delicacy.”

The new technique relies on creating soft robots that consist of two layers. The first layer is a flexible polymer that is created using 3D printing technologies and incorporates a pattern of microfluidic channels – essentially very small tubes running through the material. The second layer is a flexible shape memory polymer. Altogether, the soft robot is only 0.8 millimeters thick.

University of Colorado at Boulder News

In the quest to develop life-like materials to replace and repair human body parts, scientists face a formidable challenge: Real tissues are often both strong and stretchable and vary in shape and size.

A CU Boulder-led team, in collaboration with researchers at the University of Pennsylvania, has taken a critical step toward cracking that code. They’ve developed a new way to 3D print material that is at once elastic enough to withstand a heart’s persistent beating, tough enough to endure the crushing load placed on joints, and easily shapable to fit a patient’s unique defects.

Microalgae such as the diatom Odontella aurita and the green alga Tetraselmis striata are especially suitable as “biofactories” for the production of sustainable materials for 3D laser printing due to their high content in lipids and photoactive pigments. An international research team led by Prof. Dr Eva Blasco, a scientist at the Institute for Molecular Systems Engineering and Advanced Materials (IMSEAM) of Heidelberg University, has succeeded for the first time in manufacturing inks for printing complex biocompatible 3D microstructures from the raw materials extracted from the microalgae. The microalgae-based materials could be used in future as the basis for implants or scaffolds for 3D cell cultures.

The research has been published in Advanced Materials (“Printing Green: Microalgae-Based Materials for 3D Printing with Light”).

A new ink system, based on the microalgae Odontella aurita and Tetraselmis striata, enables the manufacturing of complex 3D microstructures with high quality and precision. (Image: Clara Vazquez-Martel)

I have a new essay out via the wonderful site Merion West. The article is based on some of my experimental writings at Oxford. I hope you’ll read and consider it. I’m highly worried life extension science isn’t moving forward fast enough!


“Sadly, biological humans are likely to be mortal for centuries more, unless a dramatic increase of both resources and life extension scientists are marshaled.”

Certain well-known gerontologists and longevity experts around the world believe that sometime in this century—probably in the next 15–50 years—medicine will likely overcome and cure most forms of disease, and even death itself. Billionaires such as Meta’s Mark Zuckerberg, Amazon’s Jeff Bezos, Alphabet’s Larry Page, and Oracle’s Larry Ellison have jumped on board, pledging billions of dollars to “conquering all disease by this century” and mortality altogether.

These business titans hope age reversal techniques via genetic editing therapies, stem cell rejuvenation, 3D bioprinting of organs, and the widespread creation of synthetic organs like artificial hearts could keep people indefinitely young and healthy. If biological human death from disease and aging are overcome, then only catastrophic accidental death—such as an airplane crash or incineration—can kill people. (Accidental death in this vein accounts for about seven percent of all deaths in the United States.)

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Big thank you to all our partners who made this project possible:
JLC3DP — Professional 3D printing and machining ► https://jlc3dp.com/?from=hacksmith.
JLCPCB photosensitive resin From ► $1 https://jlc3dp.com/help/article/197-8
Integran: Metallurgical Nano Technology ►https://www.integran.com/
Canmax Medical Imaging ► https://www.cmimri.ca/ \& @canmaxmedicalimaging on Instagram.
Dr. Kahn ► https://eterna.health/ \& @dr.akhan on Instagram.
Conestoga College ► https://www.conestogac.on.ca/
PRUSA XL 3D printer ► https://www.prusa3d.com/en/product/or
Hustle Monster Creative — Credit for building the fantastic Wolverine Suit! ► https://www.etsy.com/shop/JimsArmor.
My favorite new 3D scanner ► https://global.revopoint3d.com/produc

Learn more about the Smith Blade ►https://hacksmith.store/pages/the-smi

Watch the extended cut with real organic bone testing on Nebula ► https://nebula.tv/videos/hacksmith-co