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Archive for the ‘bioengineering’ category: Page 114

Feb 29, 2020

CRISPR’s co-developer on the revolutionary gene-editing technology’s past — and its future

Posted by in categories: bioengineering, biotech/medical, genetics

CRISPR revolutionized gene editing. Should we be worried?

Feb 28, 2020

Should we edit our DNA? An imagined future of gene editing – video

Posted by in categories: bioengineering, biotech/medical, ethics

There are decisions being made right now that could have an effect on global populations for generations to come. As part of this project, we commissioned an artist to investigate some of the themes raised in the podcasts. This work of fiction imagines a future where gene editing has become mainstream and discusses the moral, ethical and political divides that this might create.

Feb 28, 2020

Building a Positive Genetic Future for All

Posted by in categories: bioengineering, biotech/medical, evolution, food, genetics

Nearly every day, new discoveries are pushing the genetics revolution ever-forward. It’s hard to imagine it’s been only a century and a half since Gregor Mendl experimented with his peas, six decades since Watson and Crick identified the double helix, fourteen years since the completion of the human genome project, and five years since scientists began using CRISPR-cas9 for precision gene editing. Today, these tools are being used in ways that will transform agriculture, animal breeding, healthcare, and ultimately human evolution.

Common practices like in vitro fertilization (IVF) and preimplantation embryo selection make human genetic enhancement possible today. But as we learn more and more about what the genome does, we will be able to make increasingly more informed decisions about which embryos to implant in IVF in the near term and how to manipulate pre-implanted embryos in the longer-term. In our world of exponential scientific advancement, the genetic future will arrive far faster than most people currently understand or are prepared for.

Continue reading “Building a Positive Genetic Future for All” »

Feb 28, 2020

CRISPR Edited Immune Cells Successful in First U.S. Clinical Trial

Posted by in categories: bioengineering, biotech/medical

Great news.


The successful delivery of CRISPR/Cas9 modified immune cells to cancer patients represents the first U.S. clinical trial to test the gene editing approach in humans.

Researchers from the Abramson Cancer Center of the University of Pennsylvania have published data suggesting that immune cells modified using the gene editing tool CRISPR/Cas9 are able to survive and function for months following delivery to cancer patients [1].

Continue reading “CRISPR Edited Immune Cells Successful in First U.S. Clinical Trial” »

Feb 27, 2020

Hacking DNA: The Story of CRISPR, Ken Thompson, and the Gene Drive

Posted by in categories: bioengineering, biotech/medical, genetics

The very nature of the human race is about to change. This change will be radical and rapid beyond anything in our species’ history. A chapter of our story just ended and the next chapter has begun.

This revolution in what it means to be human will be enabled by a new genetic technology that goes by the innocuous sounding name CRISPR, pronounced “crisper”. Many readers will already have seen this term in the news, and can expect much more of it in the mainstream media soon. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats and is to genomics what vi (Unix’s visual text editor) is to software. It is an editing technology which gives unprecedented power to genetic engineers: it turns them into genetic hackers. Before CRISPR, genetic engineering was slow, expensive, and inaccurate. With CRISPR, genome editing is cheap, accurate, and repeatable.

Continue reading “Hacking DNA: The Story of CRISPR, Ken Thompson, and the Gene Drive” »

Feb 26, 2020

How to Battle an Epidemic? Digitize Its DNA and Share It With the World

Posted by in categories: bioengineering, biotech/medical, education, genetics

Ogba Educational Clinic


A nightmarish scene was burnt into my memory nearly two decades ago: Changainjie, Beijing’s normally chaotic “fifth avenue,” desolate without a sign of life. Schools shut, subways empty, people terrified to leave their homes. Every night the state TV channels reported new cases and new deaths. All the while, we had to face a chilling truth: the coronavirus, SARS, was so novel that no one understood how it spread or how to effectively treat it. No vaccines were in sight. In the end, it killed nearly 1,000 people.

It’s impossible not to draw parallels between SARS and the new coronavirus outbreak, COVID-19, that’s been ravaging China and spreading globally. Yet the response to the two epidemics also starkly highlights how far biotech and global collaborations have evolved in the past two decades. Advances in genetic sequencing technologies, synthetic biology, and open science are reshaping how we deal with potential global pandemics. In a way, the two epidemics hold up a mirror to science itself, reflecting both technological progress and a shift in ethos towards collaboration.

Continue reading “How to Battle an Epidemic? Digitize Its DNA and Share It With the World” »

Feb 26, 2020

Gene-editing is more error-prone than thought, new findings suggest

Posted by in categories: bioengineering, biotech/medical, genetics

The standard gene-editing tool, CRISPR-Cas9, frequently produces a type of DNA mutation that ordinary genetic analysis misses, claims new research published in the journal Proceedings of the National Academy of Sciences (PNAS). In describing these findings the researchers called such oversights “serious pitfalls” of gene editing (Skryabin et al., 2020). In all, the new results suggest that gene-editing is more error-prone than thought and, further, that identifying and discarding defective and unwanted outcomes is not as easy as generally supposed.

Gene-editing is more error-prone than thought, new findings suggest

CRISPR Enzyme on DNA (Photo: MIT News)

Feb 25, 2020

How Bionic Limbs Are Changing Lives | VICE on HBO

Posted by in categories: bioengineering, computing, cyborgs, neuroscience, transhumanism

A bionic revolution is brewing, as recent advancements in bioengineering have brought about scientific breakthroughs in rehabilitation for people with disabilities. The most cutting edge research is happening inside the human brain, where implanted technology allows people to communicate directly with computers, using their thoughts.

VICE’s Wilbert L. Cooper travels to Zurich to see the first-ever bionic Olympics and discovers a host of technologies that are expanding what it means to be human.

Continue reading “How Bionic Limbs Are Changing Lives | VICE on HBO” »

Feb 24, 2020

This man’s potentially huge medical breakthrough can’t get funding, so he’s trying something desperate

Posted by in categories: bioengineering, biotech/medical, business, existential risks

https://youtube.com/watch?v=oJcX8ch_mLg

Four years ago, Todd Rider was on top of the world. The MIT-trained bioengineer had developed a radical idea for killing viruses. Initial test results showed that his therapy, called DRACO, could kill every virus he threw it at: 15 viruses were killed in human cells, and two in mice.

It seemed like there was a chance it could be the biggest discovery in medicine since the invention of antibiotics. Enthusiastic headlines praised the potentially world-changing panacea. “Todd Rider Has a Kill Switch for Viruses,” wrote Bloomberg Businessweek. The Verge: “Killing sickness: is DRACO a doomsday device for viruses?” Time magazine declared it one of the top 50 inventions of the year.

Continue reading “This man’s potentially huge medical breakthrough can’t get funding, so he’s trying something desperate” »

Feb 22, 2020

Optimising gene editing for cancer therapy

Posted by in categories: bioengineering, biotech/medical, genetics

Gene editing holds promise for the treatment of cancers that are driven by well-characterised molecular alterations. A study now provides a proof of concept for the feasibility of in vivo gene editing to correct TERT mutations in glioblastoma, providing a platform for the direct manipulation of genetic alterations to reduce tumour growth.