Archive for the ‘bioengineering’ category: Page 12

Jun 24, 2022

The Rise of Supersoldiers — How AI Changes Everything

Posted by in categories: bioengineering, biotech/medical, chemistry, genetics, health, military, robotics/AI

Artificial Intelligence is touching almost every aspect of our lives. It’s reasonable to expect AI influence will only increase in the future. One of many fields heavily influenced by AI is the military. Particularly in the development of Supersoldiers. The notion of super-soldiers enhanced with biotechnology and cybernetics was once only possible in the realm of science fiction. But it may not be too long before these concepts become a reality.

A new worldwide arms race is pitting countries against each other to be the first to successfully create real genetically modified super soldiers by using tools such as CRISPR. Understandably many of these human enhancement technologies raise health and safety questions and it is more likely these enhancements will first gain traction in countries that do not place as much weight on ethical concerns.

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Jun 21, 2022

Patients Treated With CRISPR Still “Cured” Three Years Later

Posted by in categories: bioengineering, biotech/medical, genetics

A long-running human trial has shown that CRISPR gene editing could prove to be a highly effective way of treating serious conditions.

The trial, which was kicked off in 2019 by an international team of scientists, found that a new gene-editing therapy called exagamglogene autotemcel, or ex-cel for short, was able to essentially “cure” patients with transfusion-dependent beta thalassemia (TDT) or severe sickle cell disease (SCD), two blood disorders that are conventionally treated using blood transfusions.

It’s a promising new use of the technology. Around 100,000 Americans are affected by TDT, while SCD affects an estimated 300 to 3,000. And in a broader sense, the results suggest that tinkering with genetic code could come to be a practical, widespread new area of medicine.

Jun 16, 2022

Gene Genies: Inside The Revolutionary Biotech That Can Edit DNA Inside Living Humans

Posted by in categories: bioengineering, finance

John Leonard built Intellia Therapeutics with Jennifer Doudna, the Nobel Prize-winning scientist who pioneered gene editing technology. Intellia has figured out how to alter disease-causing genes inside patients, but before any breakthrough treatments come, it must cure itself of financial ills.

Jun 14, 2022

A “One-Time” Treatment for HIV Could Be on the Horizon

Posted by in categories: bioengineering, biotech/medical

Tel Aviv University researchers have published a new study in Nature outlining how a type of white blood cell can be engineered to secrete anti-human immunodeficiency virus (HIV) antibodies. Based on the results of this study, the team are hopeful that they will be able to produce a one-time medication for acquired immune deficiency syndrome (AIDS) and other diseases.

Gene therapy for HIV

The introduction of treatments such as anti-retroviral therapy (ART) for HIV has helped patients diagnosed with the infection to live longer and healthier lives. Patients are required to take the medicine daily in order to reduce the amount of virus in the body (viral load) so that it is undetectable. If a viral load is undetectable, patients with HIV have effectively zero risk of transmitting the virus. However, a one-time treatment for HIV, which can develop into AIDS, is still desirable to improve HIV patients’ quality of life.

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Jun 13, 2022

Mechanotransduction: Using nuclear mechanics to understand health and diseases

Posted by in categories: bioengineering, biotech/medical, health, nanotechnology

The application of mechanic forces to the cell nucleus affects the transport of proteins through the nuclear membrane, an action that controls cellular processes and could play a key role in several diseases such as cancer. These findings draw a new scenario for understanding how the mechanic forces drive the progression of cancer and open the doors to the design of potential innovative techniques—both diagnostic and therapeutic. This is the conclusion of a study published in the journal Nature Cell Biology led by lecturer Pere Roca-Cusachs, from the Faculty of Medicine and Health Sciences of the University of Barcelona, the Institute of Nanoscience and Nanotechnology of the UB (IN2UB) and the Institute for Bioengineering of Catalonia (IBEC).

The cells in the body receive mechanical stimuli from their environment and respond accordingly regarding decisions on how and when to grow, move and differentiate. The process is known as mechanotransduction and it is critically important for the cell function and for human health.

The study reveals that the direct application of force to the can affect the spatial organization of the DNA and the activity of nuclear proteins, among other functions. When invade the organs and metastasis appears, these create physical forces that are transmitted to the .

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Jun 3, 2022

Doctors Transplant Ear That Was 3D Printed With Patient’s Own Cells

Posted by in categories: bioengineering, biotech/medical, life extension

A team of scientists at a company called 3DBio Therapeutics have successfully transplanted a 3D printed ear made from the patient’s own cells, The New York Times reports.

It appears to be a first in the field of tissue engineering, according to experts, and could be the harbinger of a new era of regenerative medicine.

“It’s definitely a big deal,” Carnegie Mellon biomedical engineering researcher Adam Feinberg, who was not involved in the project, told the NYT. “It shows this technology is not an ‘if’ anymore, but a ‘when.’”.

Jun 1, 2022

Changing our DNA: ‘The age of human therapeutic gene editing is here’

Posted by in categories: bioengineering, biotech/medical

If I’ve been reading the articles right, progeria may be cured soon. Really amazing.

Advances in gene editing have brought us ever closer to fixing some of the most devastating diseases of our time, such as progeria and sickle cell disease.

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May 30, 2022

Gene-edited tomatoes could be a new source of vitamin D

Posted by in categories: bioengineering, biotech/medical, food, genetics, health, neuroscience

Tomatoes gene-edited to produce vitamin D, the sunshine vitamin, could be a simple and sustainable innovation to address a global health problem.

Researchers used gene editing to turn off a specific molecule in the plant’s genome which increased provitamin D3 in both the fruit and leaves of tomato plants. It was then converted to vitamin D3 through exposure to UVB light.

Vitamin D is created in our bodies after skin’s exposure to UVB light, but the major source is food. This new biofortified crop could help millions of people with vitamin D insufficiency, a growing issue linked to higher risk of cancer, dementia, and many leading causes of mortality. Studies have also shown that vitamin D insufficiency is linked to increased severity of infection by Covid-19.

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May 25, 2022

Nature Reviews Bioengineering

Posted by in category: bioengineering

Things are only impossible until they’re not.

May 19, 2022

Gene editing could reverse anxiety and alcohol-use disorder

Posted by in categories: bioengineering, biotech/medical, genetics, neuroscience

During that uncomfortable period between puberty and adulthood, the brain undergoes carefully orchestrated changes in gene expression and epigenetic modification. Alcohol, unfortunately, interferes with this biological architecture. Consequently, mistakes are made, and gene expression and modification do not go as planned, leaving the person vulnerable to a lifetime of psychiatric challenges, such as anxiety and alcoholism.

A team of researchers from the University of Illinois Chicago recently found they could reverse these changes in rats via gene editing. If their findings carry through to human studies, gene editing may be a potential treatment for anxiety and alcohol-use disorder in adults who were exposed to binge drinking in their adolescence.

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