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Archive for the ‘bioengineering’ category: Page 3

Dec 8, 2023

Seattle biotech hub pursues ‘DNA typewriter’ tech with $75M from tech billionaires

Posted by in categories: bioengineering, biotech/medical

A new Seattle biotech organization will be funded to the tune of $75 million to research “DNA typewriters,” self-monitoring cells that could upend our understanding of biology. The collaboration between the University of Washington, the Chan-Zuckerberg Initiative and the Allen Institute is already underway.

Called the Seattle Hub for Synthetic Biology, the joint initiative will combine the expertise of the two well-funded research outfits with that of UW Medicine, working in what UW’s Jay Shendure, scientific lead for the project, called “a new model of collaboration.”

The Hub (not to be confused with the HUB, or Husky Union Building, on UW’s campus) aims to strike a balance between a disinterested intellectual academic approach and a development-focused commercial approach. The $75 million will fund the organization for five years, with the option to renew then.

Dec 8, 2023

Next-Gen Biotech: 3 Companies Leading the Charge in Gene Therapy

Posted by in categories: bioengineering, biotech/medical

These three gene therapy stocks should get huge boosts over the long term from the use of gene editing techniques to treat diseases.

Dec 4, 2023

Bio Ink Made out of Bacteria Could Be Used to 3D Print Organs

Posted by in categories: 3D printing, bioengineering, biotech/medical, bitcoin, cryptocurrencies

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Hello and welcome! My name is Anton I’m away for a few days due to voice issues, so enjoy this older video where we talk about the incredible invention of 3D printed bio ink that could be used to print any biological tissue (in theory). 3D printed heart anyone?

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Nov 29, 2023

Synthetic Biology Exclusive Offers

Posted by in categories: bioengineering, biotech/medical

Discover our selection of discounted synthetic biology tools, perfect for advancing biomedicine, cell-cultured meats, and sustainable textiles.

Nov 29, 2023

Unlocking the future: where is gene editing going next?

Posted by in categories: bioengineering, biotech/medical

In our latest feature, we explore the future of gene editing and the challenges we must overcome to harness its full potential.

Nov 29, 2023

Explore the role of CRISPR gene editing in target validation

Posted by in categories: bioengineering, biotech/medical, genetics

Target validation is a crucial step in pre-clinical drug discovery workflows that builds confidence on the identification of a genetic target as relevant to a disease. With recent advancements, CRISPR serves as a particularly powerful tool for this process, as it enables researchers to accurately modify genes and determine their function in a variety of experimental systems.

One scientist leveraging CRISPR gene editing in this way is Dr. Panos Zalmas, Head of the Open Targets Validation Lab based at the Wellcome Sanger Institute, whose work focuses on discovering and validating new putative disease targets for the development of safe and effective medicines.

In this SelectScience® interview, we speak with Zalmas to learn how he is working to improve the rate of target adoption into drug discovery pipelines across therapy areas such as oncology, neurodegeneration, and immunology and inflammation. Here, Zalmas explains the importance of gene editing in his target validation workflows and highlights how CRISPR technologies in particular are key to the success of drug discovery.

Nov 28, 2023

Patient Dies After Being Gene-Edited to Have Lower Cholesterol

Posted by in categories: bioengineering, biotech/medical, genetics

Researchers have been able to reduce dramatically the level of bad cholesterol in human subjects after injecting them with an experimental gene editing treatment, according to the science journal Nature, which is the first time this technique, called base editing, has been done on humans.

But at least one person died after receiving an infusion, prompting a round of safety concerns.

In the clinical trial, 10 subjects with congenitally high levels of bad cholesterol, aka low-density lipoprotein (LDL), were given an injection of VERVE-101, a gene-editing treatment that uses the base editing technique. This treatment then turned off the gene for the protein PCSK9, which is found in the liver and regulates LDL. High levels of LDL can lead to coronary heart disease.

Nov 26, 2023

CRISPR-Cas9 Gene Editing Is On The Cusp Of Something Big

Posted by in categories: bioengineering, biotech/medical

Discover the power of gene editing, including the widely used CRISPR-Cas9 technology, and explore major publicly traded CRISPR companies.

Nov 25, 2023

Gene editing will change medicine—and maybe health investing too

Posted by in categories: bioengineering, biotech/medical, chemistry, genetics, health

The groundbreaking gene-editing technology known as Crispr, which acts like a molecular pair of scissors that can be used to cut and modify a DNA sequence, has moved rather quickly from the pages of scientific journals to the medical setting. Earlier this month, about three years after Jennifer Doudna and Emmanuelle Charpentier won the Nobel Prize in Chemistry for describing how bacteria’s immune system could be used as a tool to edit genes, regulators in the U.K. approved the first Crispr-based treatment for sickle cell disease and beta-thalassemia patients. The treatment, from Vertex Pharmaceuticals and Crispr Therapeutics, could be approved by the U.S. Food and Drug Administration early next month for sickle cell patients.

While many obstacles lie ahead for the nascent field, such as how to pay for treatments that typically cost more than $1 million, these regulatory approvals are just the start as newer gene-editing technologies such as base and prime editing make their way through human studies. In an interview, Prof. Doudna says the approval is “a turning point in medicine because it really shows how genome editing can be used as a one-and-done cure for disease.”

Gene editing is part of a broader therapeutic revolution that encompasses genetic and cellular medicine. The pills and injections we are all familiar with generally target proteins or pathways in the body to treat disease. With gene and cell therapy, we can now target the root cause of disease, sometimes curing patients.

Nov 24, 2023

Future Business Tech

Posted by in categories: augmented reality, bioengineering, biological, blockchains, genetics, Ray Kurzweil, robotics/AI, singularity, transhumanism

This video explores the future of the world from 2030 to 10,000 A.D. and beyond…Watch this next video about the Technological Singularity: https://youtu.be/yHEnKwSUzAE.
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0:00 2030
12:40 2050
39:11 2060
49:57 2070
01:04:58 2080
01:16:39 2090
01:28:38 2100
01:49:03 2200
02:05:48 2300
02:20:31 3000
02:28:18 10,000 A.D.
02:35:29 1 Million Years.
02:43:16 1 Billion Years.

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