Lifeboat Foundation

2 big points from this. 1. Plasma dilution does reverse aging but a bit and the next question will be can it be done over and over to make you younger in steps. 2. She mentions wrapping up human test results and hopes to give the results at some point.

At the EARD 2021 conference, Dr. Irina Conboy discusses the rejuvenating effects of plasma dilution in old mice. Dr. Conboy also explains why she believes that the path of rejuvenation is through tissue maintenance and repair, not preventing tissue damage.

Continue reading “Dr. Irina Conboy — Rejuvenating Effects of Plasma Dilution” »

A combination of soon-to-be released Biotechnology is expected to extend of lifespans almost tenfold with the help through emerging technologies such as CRISPR or Senolytics. These Anti Aging treatments are meant to stop and even reverse the aging process so that anyone could get young and healthy again. Many companies such as SENS or Jeff Bezos, but even countries like Japan are working on it to deal with an aging population.
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TIMESTAMPS:
00:00 A new Beginning for Longevity.
00:44 Direct Gene Editing.
02:32 Anti Aging Vaccines.
04:44 Longevity Gene Therapy.
07:39 How does Aging work?
09:49 Last Words.
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#longevity #biotech #futurology

Despite the fact that floating around in space looks like a certified blast, it’s not something the human body is optimized for. In order to make these trips possible, scientists are going to have to figure out how to mimic Earth’s gravity in space.
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We evolved with gravity constantly pulling on us at a rate of about 9.8 m/s2, or 1 g. Our bodies are built in a way that takes that into account. Our rigid bones can hold us up, our cardiovascular system can pump blood to and from our extremities, our vestibular system in our ears keeps us balanced, and so on. Our bodies are also good at adapting to our needs, which means when you take gravity away the body starts to change. Bones lose mineral density, hearts weaken, and the vestibular system shuts off because suddenly there is no “up” anymore. So long as the body stays in space these changes aren’t really a problem, but coming back to Earth and readapting to 1 g can be painful and disorienting.

Continue reading “Humans Might Need Artificial Gravity for Space Travel” »

Gene editing approaches promise to treat a range of diseases, but delivering editing agents to cells in animal models and humans safely and efficiently has proven challenging. Now, researchers led by a team at the Broad Institute of MIT and Harvard have developed a way to get gene editing proteins inside cells in animal models with high enough efficiency to show therapeutic benefit.

In new work published in Cell, the team shows how they have engineered virus-like particles to deliver base editors — proteins that make programmable single-letter changes in DNA — and CRISPR-Cas9 nuclease, a protein that cuts DNA at targeted sites in the genome. In collaboration with ​​research teams led by Krzysztof Palczewski at the University of California, Irvine, and Kiran Musunuru at the Perelman School of Medicine at the University of Pennsylvania, the team used their particles, called engineered virus-like particles (eVLPs), to disable a gene in mice that can be associated with high cholesterol levels, and partially restored visual function to mice harboring a mutation that causes genetic blindness.

Researchers have developed virus-like particles that deliver therapeutic levels of protein to animal models of disease.

Continue reading “Engineered particles efficiently deliver gene editing proteins to cells in mice” »

A man with terminal heart disease is responding well three days after being given a genetically modified pig heart in a first-of-its-kind surgery, his doctors reported on Monday.
The surgery, performed by a team at the University of Maryland Medicine in the United States, is among the first to demonstrate the feasibility of a pig-to-human heart transplant, a field made possible by new gene editing tools.
If proven successful, scientists hope pig organs could help alleviate shortages of donor organs.
For David Bennett, a 57-year-old from Maryland, the heart transplant was his last option.

Al Jazeera’s Barbara Angopa reports.

Continue reading “US man recovering after ‘breakthrough’ pig heart transplant” »

Bio-Printing Complex Human Tissues & Organs — Dr. Anthony Atala, MD — Director, Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, Wake Forest University.

Dr. Anthony Atala, MD, (https://school.wakehealth.edu/Faculty/A/Anthony-Atala) is the G. Link Professor and Director of the Wake Forest Institute for Regenerative Medicine, and the W. Boyce Professor and Chair of Urology.

Continue reading “Dr Anthony Atala, MD — Director, Wake Forest Inst for Regenerative Medicine — Printing Human Tissues” »

The first humans emerged on Earth about 4 million years ago, but new evidence from the study of human evolution has revealed compelling evidence that a small group of these hominins was genetically modified by ancient alien visitors to create the first Homo sapiens.

Researcher and author Daniella Fenton has thoroughly analyzed humanity’s earliest origins and its sudden acceleration in brain development nearly 800,000 years ago, and this research has led to a major revelation.

“Homo sapiens is the creation of ancient astronauts who came through a wormhole in the Pleiades star cluster more than 780,000 years ago.”

Continue reading “Did aliens genetically engineer humans 780,000 years ago?” »

“The potential to deliver ‘one shot cures’ is one of the most attractive aspects of gene therapy, genetically-engineered cell therapy and gene editing. However, such treatments offer a very different outlook with regard to recurring revenue versus chronic therapies,” analyst Salveen Richter wrote in the note to clients Tuesday. “While this proposition carries tremendous value for patients and society, it could represent a challenge for genome medicine developers looking for sustained cash flow.”

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Goldman Sachs warns sales from the most successful disease treatments are difficult to maintain.

Continue reading “Goldman Sachs asks in biotech research report: ‘Is curing patients a sustainable business model?’” »

The targeted gene used for the edit is conserved across evolution, suggesting the technique could work in more animals than just mice.