St. Jude’s Liz Kellogg, Ph.D., uses cryo-EM to study programmable transposons for targeted gene therapies, including potential new treatments for cystic fibrosis.
The future of CRISPR involves clinical trials focused on treatment for blood diseases and cancers, cardiovascular disease, T1D, and HIV.
As an innovative concept in materials science and engineering, the inspiration for self-healing materials comes from living organisms that have the innate ability to self-heal. Along this line, the search for self-healing materials has been generally focused on “soft” materials like polymers and hydrogels. For solid-state metals, one may intuitively imagine that any form of self-healing will be much more difficult to achieve.
A novel method utilising genes in our body to perform long-sequence DNA recombination and editing, called the RNA bridge, has been discovered and reported by genetic engineers. ThePrint #̦PureScience, Sandhya Ramesh explains the findings and implications.
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Chinese scientists have developed a method using genetic engineering to potentially enhance brain-computer interface (BCI) technology by enlarging neurons for better signal transmission.
The researchers, with the Chinese Academy of Sciences’ National Centre for Nanoscience…
Gene sequence could be implanted with electrodes to make neurons larger and easier to ‘read’ in quest for better mind control of devices.
Continue reading “Chinese researchers’ implant genetically modifies brain cells for neuron growth” »
A nanoparticle formulation, using oligonucleotide chemistry, able to release a gene editing system with single cell resolution after near infrared laser activation. The full potential of the formulation was demonstrated in the brain after intracerebral and intranasal administrations. The spot of the laser defined the region of gene editing.
Noninvasive braincomputer interfaces could vastly improve brain computer control.
Over the past two decades, the international biomedical research community has demonstrated increasingly sophisticated ways to allow a person’s brain to communicate with a device, allowing breakthroughs aimed at improving quality of life, such as access to computers and the internet, and more recently control of a prosthetic limb. DARPA has been at the forefront of this research.
The state of the art in brain-system communications has employed invasive techniques that allow precise, high-quality connections to specific neurons or groups of neurons. These techniques have helped patients with brain injury and other illnesses. However, these techniques are not appropriate for able-bodied people. DARPA now seeks to achieve high levels of brain-system communications without surgery, in its new program, Next-Generation Nonsurgical Neurotechnology (N3).
Continue reading “Nonsurgical Neural Interfaces Could Significantly Expand Use of Neurotechnology” »
There are different types of biotechnology protocols for genome/gene editing (GE), but the preferred one is the Clustered Regularly Interspaced Short Palynodromic Repeat (CRISPR) Cas9 system. Advantages include precision, the ability to design variants tailored to needs, and optimal operational cost and time.
University of Arizona researchers have developed an ‘attomicroscopy’ technique using a novel ultrafast electron microscope that captures moving electrons in unprecedented detail, paving the way for significant scientific breakthroughs in physics and other fields.
Imagine having a camera so advanced that it can capture freeze-frame images of a moving electron—an object so fast it could orbit the Earth multiple times in just a second. Researchers at the University of Arizona have developed the world’s fastest electron microscope capable of this remarkable feat.
They believe their work will lead to groundbreaking advancements in physics, chemistry, bioengineering, materials sciences, and more.
With investments, approvals, and revenues on the rise, gene editing therapy is increasingly able to address delivery and accessibility challenges.
