Lifeboat Foundation

Can the origin of life be explained with quantum mechanics? And if so, are there quantum algorithms that could encode life itself?

We’re a little closer to finding out the answers to those big questions thanks to new research carried out with an IBM supercomputer.

Encoding behaviours related to self-replication, mutation, interaction between individuals, and (inevitably) death, a newly created quantum algorithm has been used to show that quantum computers can indeed mimic some of the patterns of biology in the real world.

Continue reading “Scientists Just Created Quantum Artificial Life For The First Time Ever” »

https://www.youtube.com/watch?v=n4YtQ-N_t84

When listening to world science festival’s latest episode on youtube, Pondering the Imponderables: The Biggest Questions of Cosmology, I found myself to be most in line with George F.R. Ellis’ line of thinking overall.

Big Bang cosmology, chemical and biological evolutionary theory, and associated sciences have been extraordinarily successful in revealing and enabling us to understand the development of the.

Continue reading “On the Nature of Causality in Complex Systems, George F.R. Ellis” »

Fuel cells have long been viewed as a promising power source. These devices, invented in the 1830s, generate electricity directly from chemicals, such as hydrogen and oxygen, and produce only water vapor as emissions. But most fuel cells are too expensive, inefficient, or both.

In a new approach, inspired by biology and published today (Oct. 3, 2018) in the journal Joule, a University of Wisconsin-Madison team has designed a fuel cell using cheaper materials and an organic compound that shuttles electrons and protons.

In a traditional fuel cell, the electrons and protons from hydrogen are transported from one electrode to another, where they combine with oxygen to produce water. This process converts chemical energy into electricity. To generate a meaningful amount of charge in a short enough amount of time, a catalyst is needed to accelerate the reactions.

Continue reading “New fuel cell concept brings biological design to better electricity generation” »

In a new scientific article, researchers at Uppsala University describe how, using a completely new method, they have synthesised an artificial enzyme that functions in the metabolism of living cells. These enzymes can utilize the cell’s own energy, and thereby enable hydrogen gas to be produced from solar energy.

Hydrogen gas has long been noted as a promising energy carrier, but its production is still dependent on fossil raw materials. Renewable hydrogen gas can be extracted from water, but as yet the systems for doing so have limitations.

In the new article, published in the journal Energy and Environmental Science, an interdisciplinary European research group led by Uppsala University scientists describe how artificial enzymes convert solar energy into hydrogen gas. This entirely new method has been developed at the University in the past few years. The technique is based on photosynthetic microorganisms with genetically inserted enzymes that are combined with synthetic compounds produced in the laboratory. Synthetic biology has been combined with synthetic chemistry to design and create custom artificial enzymes inside living organisms.

Continue reading “Artificial enzymes convert solar energy into hydrogen gas” »

A fluorescent molecule whose luminosity depends upon how fast it can rotate is helping researchers measure how viscous the fluid is inside different parts of a cell.

“There’s a lot of interest in the biophysical field in developing chemical probes that can be used to characterize the environment inside a cell or any kind of biological compartment,” says Peter Bond, from A*STAR’s Bioinformatics Institute.

Researchers from the United Kingdom and Singapore—including A*STAR scientists such as Bond’s team who led the computational arm of the project—have modeled, developed and tested a molecule comprising two parts; a genetic probe designed to home in on particular proteins, so it can be directed to wherever in a cell that protein is found; and a molecular rotor—a fluorescent molecule whose fluorescence lasts longer, the slower it spins. A*STAR researchers simulated how this molecule would perform in different microenvironments at scales of millionths or even billionths of a meter.

Continue reading “Fluorescent molecule could shed light on the inner workings of the cellular environment” »

What’s up with these 2 factions trying to split reality in 2? 🤔.

Are you a multispecies mix of human and microbial bits – or is there a fuzzy boundary between you and your tiny companions?

👀

The GTPases constitute a very large protein family, whose members are involved in the control of cell growth, transport of molecules, synthesis of other proteins, etc. Despite the many functions of the GTPases, they follow a common cyclic pattern (Figure 1). The activity of the GTPases is regulated by factors that control their ability to bind and hydrolyse guanosine triphosphate (GTP) to guanosine diphosphate (GDP). So far, it has been the general assumption that a GTPase is active or “on” when it is bound to GTP and inactive or “off” in complex with GDP. The GTPases are therefore sometimes referred to as molecular “switches.”

The bacterial translational elongation factor EF-Tu is a GTPase, which plays a crucial role during the synthesis of proteins in bacteria, as the factor transports the amino acids that build up a cell’s proteins to the cellular protein synthesis factory, the ribosome. Previous structural studies using X-ray crystallography have shown that EF-Tu occurs in two markedly different three-dimensional shapes depending on whether the factor is “on” (i.e. bound to GTP) or “off” (i.e. bound to GDP) (Figure 2). The binding of GTP/GDP have therefore always been thought to be decisive for the factor’s structural conformation.

Continue reading “Molecular switches are not just ‘on’ or ‘off’” »

Illuminating mathematics, physics, biology and computer science research through public service journalism.

Some patterns of electrical activity generated by the brain during sleep are inherited, according to a study of teenage twins published in JNeurosci. Pinpointing the relative contributions of biology and experience to sleep neurophysiology could inform therapies for numerous psychiatric disorders in which alterations in brain activity during sleep can be detected.