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Category: biotech/medical – Page 106

Newly developed organic compounds can serve as highly sensitive oxygen sensors

Researchers at Kaunas University of Technology (KTU), Lithuania, have developed new organic compounds that act as highly sensitive oxygen sensors. These sensors can accurately detect even the slightest amounts of oxygen in the environment—information that is crucial in situations where oxygen concentration can determine the success of a process or even a person’s life.

The sensors can be applied in medicine; for example, in diagnosing tumor hypoxia, a condition in which there is almost no oxygen around a tumor; in the food industry, to check whether packaging has lost its seal; and in biotechnology, to precisely monitor cell cultivation processes.

Moreover, their performance can be observed with the naked eye, while their record-high sensitivity ensures rapid and reliable detection. The study is published in the journal Sensors and Actuators B: Chemical.

Clocks created from random events can probe ‘quantumness’ of universe

A newly discovered set of mathematical equations describes how to turn any sequence of random events into a clock, scientists at King’s College London reveal. The paper is published in the journal Physical Review X.

The researchers suggest that these formulas could help to understand how cells in our bodies measure time and to detect the effects of quantum mechanics in the wider world.

Studying these timekeeping processes could have far-reaching implications, helping us to understand proteins with rhythmic movements which malfunction in motor neuron disease or chemical receptors that cells use to detect harmful toxins.

Scientists Grow “Gold Quantum Needles” for Sharper Biomedical Imaging

Potential applications range from biomedical imaging to the conversion of light energy. University of Tokyo researchers Shinjiro Takano, Yuya Hamasaki, and Tatsuya Tsukuda have directly imaged how the geometric arrangement of atoms in gold nanoclusters develops at the very earliest stages of growth

Rice research team on quest to engineer computing systems from living cells

Rice University biosciences professor Matthew Bennett has received a $1.99 million grant from the National Science Foundation to lead research on engineered bacterial consortia that could form the basis of biological computing systems. The four-year project will also involve co-principal investigators Kirstin Matthews, Caroline Ajo-Franklin and Anastasios Kyrillidis from Rice along with Krešimir Josić from the University of Houston. The research team aims to develop platforms that integrate microbial sensing and communication with electronic networks, paving the way for computing systems constructed from living cells instead of traditional silicon-based hardware.

The project highlights the growing potential of synthetic biology, where microbes are examined not just as living organisms but as processors of information. If successful, Bennett’s research could accelerate medical diagnostics, environmental monitoring and the development of next-generation computing applications.

“Microbes are remarkable information processors, and we want to understand how to connect them into networks that behave intelligently,” Bennett said. “By integrating biology with electronics, we hope to create a new class of computing platforms that can adapt, learn and respond to their environments.”

Chinese researchers on Tuesday unveiled their self-developed world’s first “bone glue”

Material capable of securely bonding fractured bone fragments within 2–3 minutes in a blood-rich environment.

ในช่วงไม่กี่ปีที่ผ่านมา จีนได้แสดงศักยภาพด้านวิทยาศาสตร์การแพทย์อย่างต่อเนื่อง หนึ่งในผลงานที่ได้รับความสนใจระดับโลกคือการพัฒนาวัสดุชีวภาพชนิดใหม่ที่เรียกว่ากาวกระดูก (Bine Glue) ที่สามารถเชื่อมกระดูกที่หักให้ติดกันได้ภายในระยะเวลาเพียง 3 นาที

Portable light-based brain monitor shows promise for dementia diagnosis

Early and accurate diagnosis of dementia remains a major challenge. Standard approaches such as MRI and PET scans can provide valuable information about brain structure and function, but they are expensive, not always accessible, and often too expensive for repeated use.

A team of researchers in the UK has now demonstrated that a compact, noninvasive technology—broadband (bNIRS)—may offer a new way to detect brain changes linked to Alzheimer’s disease, even in the early stages.

In this pilot study reported in the Journal of Biomedical Optics, scientists used bNIRS to monitor both blood oxygenation and brain metabolism in response to .

‘More than just an image’: New algorithm can extract hyperspectral info from conventional photos

Professionals in agriculture, defense and security, environmental monitoring, food quality analysis, industrial quality control, and medical diagnostics could benefit from a patent-pending innovation that opens new possibilities of conventional photography for optical spectroscopy and hyperspectral imaging.

Young Kim, Purdue University professor, University Faculty Scholar and Showalter Faculty Scholar, and postdoctoral research associate Semin Kwon of the Weldon School of Biomedical Engineering created an algorithm that recovers detailed spectral information from photographs taken by conventional cameras. The research combines computer vision, color science and optical spectroscopy.

“A photograph is more than just an image; it contains abundant hyperspectral information,” Kim said. “We are one of the pioneering research groups to integrate computational spectrometry and spectroscopic analyses for biomedical and other applications.”

Fat molecules and water interact in surprising ways within collagen fibrils

Researchers from the Faculty of Natural Sciences at Chemnitz University of Technology have discovered fat molecules in natural collagen fibrils, the main component of connective tissue. Their research, published in Soft Matter, shows how fats affect the mechanical properties and water content of collagen fibrils.

Collagen fibrils are the basic building blocks of skin, tendons, ligaments, and bones. They hold our bodies together. Fats and oils have long been used to soften and protect leather, which consists of collagen molecules. However, it is not known how many fat molecules are contained in natural collagen fibrils.

Knowing the precise chemical composition of collagen fibrils is important for understanding biochemical processes involved in tissue growth, aging, and disease. In chemistry, the various molecular components are usually separated to study the properties of pure substances. However, contain thousands of different chemical molecules, all of which are likely important.

RNA technology ‘hacks’ into phage replication, offering new insights into molecular interactions

Bacteriophages, or phages for short, are viruses that infect bacteria. Using phages therapeutically could be very useful in fighting antibiotic-resistant pathogens, but the molecular interactions between phages and host bacteria are not yet sufficiently understood. Jörg Vogel’s research group at the Helmholtz Institute for RNA-based Infection Research (HIRI) and the Institute of Molecular Infection Biology (IMIB) in Würzburg has now succeeded in specifically interfering with phage reproduction using a molecular tool called antisense oligomers (ASOs).

According to the researchers, this innovative RNA technology offers new insights into the molecular world of phages and is expected to advance the development of future therapeutic applications. The study has been published in the journal Nature.

Like humans, bacteria have to cope with viruses—known as bacteriophages, or phages for short. Phages invade bacteria, hijack their cellular machinery, multiply, and cause the bacterial cell to burst. This releases new phages, which then go on to infect other bacteria. Phages are harmless to humans because they target only bacteria. They are also quite selective: Most phages are specialized in infecting specific host bacteria, including bacterial pathogens.

Permeable inspection of pharmaceuticals: Real-time tablet quality inspection system developed

Led by Assistant Professor Kou Li, a research group at Chuo University, Japan, has developed a synergetic strategy among non-destructive terahertz (THz)–infrared (IR) photo-monitoring techniques and ultrabroadband sensitive imager sheets toward demonstrating in-line real-time multi-scale quality inspections of pharmaceutical agent pills.

The paper has been published in Light: Science & Applications.

While non-destructive in-line monitoring at manufacturing sites is essential for safe distribution cycles of pharmaceuticals, efforts are still insufficient to develop analytical systems for detailed dynamic visualization of foreign substances and material composition in target pills.

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